73 citations
,
January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
14 citations
,
September 2006 in “OMICS A Journal of Integrative Biology” DNA microarrays help study skin diseases and biology, leading to advancements in understanding and treatment.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
182 citations
,
May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
25 citations
,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
7 citations
,
January 2009 in “Biological & pharmaceutical bulletin” Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.
15 citations
,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
April 2012 in “Cancer Research” Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.
29 citations
,
October 2016 in “Cell death and differentiation” ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
250 citations
,
November 2003 in “The Journal of Cell Biology” BMP receptor IA is essential for proper hair cell differentiation in mice.
42 citations
,
August 1995 in “British journal of dermatology/British journal of dermatology, Supplement” RXR-alpha is strongly expressed in both normal and psoriatic skin and may help in skin cell differentiation and hair growth.
July 2024 in “Journal of Investigative Dermatology” Versican in dermal papilla cells is crucial for healthy hair growth.
September 2014 in “Genes and Cells” Genetically modified umbilical cord blood cells improved skin wound healing in rats.
14 citations
,
March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
94 citations
,
October 1994 in “The Journal of Cell Biology” Too much keratin 16 in mice skin causes abnormal skin thickening and structure.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
50 citations
,
October 2011 in “Archives of Biochemistry and Biophysics” Vitamin D receptor is essential for healthy hair growth.
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Suppressing very long chain fatty acids is linked to skin cancer.
139 citations
,
August 2006 in “Molecular and Cellular Biology” Rac1 is vital for hair follicle health but not needed for skin maintenance.
22 citations
,
April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
6 citations
,
April 2022 in “Advanced Pharmaceutical Bulletin” Cefazolin-loaded nanoparticles in nanofibers can help heal wounds and support regeneration.
9 citations
,
April 2006 in “American Journal of Pathology” SGK3 is essential for proper hair growth and health.
21 citations
,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
August 2017 in “Academic Commons (Stony Brook University)” Acer1 is essential for skin health and affects hair growth and skin cancer risk.
April 2018 in “Journal of Investigative Dermatology” Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
146 citations
,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
26 citations
,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Androgens increase growth factors in skin cells, which may lead to acne.