research The amazing miniorgan: Hair follicle
Understanding hair follicles can lead to new treatments for hair loss and skin tumors.
Search
for
Sort by
Research
930-960 / 1000+ results research Collagen XVIIα1 in skin and hair aging: Mechanisms, stem cell niche regulation, and translational strategies
Collagen XVIIα1 decline causes skin and hair aging.
research Single‐Cell RNA Sequencing Highlights a Contribution of Human Amniotic Mesenchymal Stem Cells‐Derived Exosomes to Androgenetic Alopecia
Human amniotic stem cell exosomes may effectively treat hair loss by promoting hair regrowth.
research Stem-cell therapy in dermatology – Challenges and opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review
Stem cell treatments show promise for hair loss but need more research.
research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes
Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
research The stem cell niche
Stem cell niches are essential for tissue health and repair.
research N1-acetylspermidine is a determinant of hair follicle stem cell fate
N1-acetylspermidine promotes hair follicle stem cell self-renewal.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Towards a molecular understanding of hair loss and its treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
research A direct link betweenPrss53, hair curvature, and skeletal dysplasia
The gene Prss53 affects hair shape and bone development in rabbits.
research Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells
Stat3 activation increases hair follicle progenitors but reduces bulge region stem cells.
research Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle
Thyroxine can adjust the body's peripheral clock, potentially helping treat clock-related diseases.
research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration
Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types
NF-κB is crucial for different stages and types of hair growth in mice.
research Alopecia areata
Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations
Plucking some hairs can trigger nearby unplucked hairs to grow back more due to a collective response.
research Nerve dependence in tissue, organ, and appendage regeneration
Nerves are crucial for the regeneration of various body parts in many animals.
research Mechanical stretch induces hair regeneration through the alternative activation of macrophages
Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
research The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization
The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis
TCF/Lef1 activity is essential for proper skin cell development and renewal.
research Epidemiology of skin cancer in the mature patient
Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
research The cycling hair follicle as an ideal systems biology research model
The hair follicle is a great model for research to improve hair growth treatments.