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research Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes

January 2022 in “Journal of St. Marianna University”

Substances from human hair cells can affect hair loss-related genes, potentially leading to new treatments for baldness.

Generation of Human Hair Follicle Organoids In Vitro and Ex Vivo by Co-Culture of Primary Human Hair Matrix Keratinocytes and Dermal Papilla Fibroblasts

research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

June 2020 in “Journal of Investigative Dermatology”

Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.

Influence of Human Placenta Extracts on Prostanoids Production in Cultured Hair Follicle-Derived Keratinocytes: The Possibility of Pharmaceutical Regenerative Medicine

research Influence of Human Placenta Extracts on Prostanoids Production in Cultured Hair Follicle-Derived Keratinocytes: The Possibility of Pharmaceutical Regenerative Medicine

January 2020 in “Journal of St. Marianna University”

Human placenta extract may promote hair growth by affecting certain lipid compounds.

research Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

427 citations , April 2008 in “Nature Protocols”

research Two- and Three-Dimensional Culture of Keratinocyte Stem and Precursor Cells Derived from Primary Murine Epidermal Cultures

28 citations , September 2011 in “Stem Cell Reviews and Reports”

research 54622 A characterization of US patients with keratinocyte carcinomas using DataDerm

September 2024 in “Journal of the American Academy of Dermatology”

Most U.S. keratinocyte carcinoma patients are older white males living in urban areas.

research Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes

46 citations , July 2015 in “Wound repair and regeneration”

Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.

research Culture of hair matrix and follicular keratinocytes

26 citations , July 1993 in “Journal of Investigative Dermatology”

research Roles of Testosterone in the Growth of Keratinocytes Through Bald Frontal Dermal Papilla Cells

21 citations , January 1999 in “Endocrine”

research Analysis of proliferation, apoptosis and keratin expression in cultured normal and immortalized human buccal keratinocytes

27 citations , February 2003 in “European Journal Of Oral Sciences”

SVpgC2a cells show abnormal growth and keratin changes, modeling early cancer development.

research Ginsenosides Rb₁ and Rd Regulate Proliferation of Mature Keratinocytes Through Induction of p63 Expression in Hair Follicles

15 citations , September 2012 in “PTR. Phytotherapy research/Phytotherapy research”

Ginsenosides Rb₁ and Rd may help prevent hair loss by promoting hair cell growth.

research Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle

1 citations , January 2022 in “Cell Biology International”

Changing CDK4 levels affects the number of stem cells in mouse hair follicles.

research Novel Technique for Retention of Cell Suspension in Melanocyte–Keratinocyte Transplantation Procedure Using Glued Nylon Suture or Mesh

February 2018 in “Dermatologic Surgery”

research T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts

2 citations , April 2025 in “Journal of Investigative Dermatology”

research Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest it Evolved from Keratinocyte Keratins.

238 citations , May 1989 in “Journal of Investigative Dermatology”

research GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis

24 citations , December 2013 in “Archives of Dermatological Research”

research Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration

8 citations , August 2023 in “Journal of Investigative Dermatology”

research Regulatory effect of 4-O-methylhonokiol on TGF-β1-induced cell cycle arrest in human keratinocyte cell line (HaCaT)

August 2011 in “Planta Medica”

4-O-methylhonokiol from Magnolia Officinalis may promote hair growth by interfering with TGF-β1 effects in skin cells.

research An estrogen receptor pathwayregulates thetelogen-anagen hair follicle transition andinfluences epidermal cell proliferation (epidermis/estrogen/keratinocyte/differentiation/mesenchymal

January 1996

The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.

research A Murine Monoclonal Antibody (VM-1) Against Human Basal Cells Inhibits the Growth of Human Keratinocytes in Culture

25 citations , April 1985 in “Journal of Investigative Dermatology”

research Heterozygous deletion of the NSDHL gene in an Appenzeller Mountain Dog with verrucous epidermal keratinocytic nevi

1 citations , April 2024 in “Animal Genetics”

A genetic defect in an Appenzeller Mountain Dog caused skin issues, improved with ketoconazole, showing the importance of advanced genetic testing.

research Characterization of Hair Follicle Bulge in Human Fetal Skin: The Human Fetal Bulge Is a Pool of Undifferentiated Keratinocytes

96 citations , December 1995 in “Journal of Investigative Dermatology”

research Wound Healing: A Cellular Perspective

1160 citations , November 2018 in “Physiological Reviews”

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

research Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis

1010 citations , August 2000 in “Cell”

Hair follicle stem cells can form both hair follicles and skin.

research Cellular and molecular mechanisms of repair in acute and chronic wound healing

908 citations , July 2015 in “British Journal of Dermatology”

Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.

research Wound repair at a glance

733 citations , September 2009 in “Journal of Cell Science”

Wound healing is a complex, multi-phase process involving various cells and activities to repair skin damage.

research Mechanisms regulating skin immunity and inflammation

610 citations , April 2014 in “Nature Reviews Immunology”

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

research Reversible Activation of c-Myc in Skin

467 citations , May 1999 in “Molecular Cell”

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

research Hair Follicle Pigmentation

450 citations , January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair color is determined by melanin produced and transferred in hair follicles.

research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

441 citations , May 1996 in “Journal of Cell Science”

Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.

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