482 citations
,
June 1979 in “Proceedings of the National Academy of Sciences” Keratins provide structural strength in epithelial cells and help identify cell origins.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
5 citations
,
January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
15 citations
,
November 2009 in “Journal of Comparative Pathology” Epidermolysis bullosa in calves was not caused by mutations in the keratin genes bKRT5 and bKRT14.
December 2024 in “Genome Biology and Evolution” Snakes and worm lizards lost claw proteins due to similar evolutionary changes.
January 1996 in “TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES” Brown bear skin has two main layers, with the thickest skin on the back and thinnest on the belly.
9 citations
,
September 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Pseudofolliculitis cutis causes painful skin bumps and needs proper shaving and treatments to manage.
38 citations
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July 2004 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
54 citations
,
November 1994 in “Differentiation” Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.
64 citations
,
March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
38 citations
,
July 1993 in “Journal of Investigative Dermatology” 4 citations
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January 2019 in “Indian Dermatology Online Journal” The term "Porokeratotic Adnexal Ostial Nevus" is suggested as a more appropriate name.
2 citations
,
August 2016 in “Journal of Investigative Dermatology”
6 citations
,
January 2000 in “Dermatology” A girl's severely tangled hair couldn't be fixed and had to be cut due to a rare condition called plica neuropathica.
13 citations
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January 2018 in “Advances in experimental medicine and biology”
15 citations
,
January 2012 in “Journal of Veterinary Science” Different dog breeds have varying skin thickness and protein expression in their skin.
135 citations
,
November 1987 in “Differentiation” Outer root sheath cells consistently express certain keratins influenced by their environment.
11 citations
,
January 2005 in “Brazilian Journal of Medical and Biological Research” Hairless USP mice have enlarged skin cysts as they age.
January 2022 in “Indian dermatology online journal” A baby with a skin condition improved with treatment but developed a rare form of the condition affecting only his trunk.
57 citations
,
January 1987 in “Journal of Biological Chemistry” Different keratins have unique expression patterns in mouse skin cells.
January 2005 in “Australian viticulture” Different tissues in cows have different types of cytokeratins.
January 2026 in “Indian Journal of Ophthalmology - Case Reports” Trichilemmal cysts can appear on children's eyelids and may be mistaken for other conditions.
13 citations
,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
15 citations
,
May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
41 citations
,
July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.
34 citations
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December 1984 in “Journal of Cutaneous Pathology” Monilethrix hair issues are due to problems in the hair's internodes.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting the Hoxc13 gene in frogs shows its crucial role in developing skin structures similar to hair.
December 2010 in “HAL (Le Centre pour la Communication Scientifique Directe)” The cornea develops independently of the lens, following its own default pathway.
70 citations
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December 2008 in “Cancer Research” CXCR2 in skin cells promotes tumor growth.