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690-720 / 1000+ resultsresearch Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
TCDD changes skin cell growth and keratin production in mice.
research The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research The lipide composition of epidermis and dermis of mice undergoing carcinogenesis by methylcholanthrene.
Cholesterol and phospholipids increase in mouse skin during cancer development, with differences between male and female skin.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research Erythrokeratodermia Variabilis
A 4-year-old girl was diagnosed with erythrokeratodermia variabilis after other treatments failed.
research Histochemistry of the porcine pilosebaceous unit
Porcine and human pilosebaceous units are very similar.
research BH11 Cutis verticis gyrata associated with chronic traction
Tight hairstyles can cause a rare scalp condition with thick skin folds.
research The surface and internal features of pubic hair: A comparative study with those of scalp hair
Pubic hair has a thicker, more protective outer layer than scalp hair, possibly due to evolution.
research Regeneration of Epidermal and Dental Tissues, Lens and Cornea
Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
research Severe Abnormalities in the Oral Mucosa Induced by Suprabasal Expression of Epidermal Keratin K10 in Transgenic Mice
Abnormal keratin expression in mice causes severe oral issues, affecting feeding.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Keratins: Dynamic, flexible structural proteins of epithelial cells
Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
research Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex
Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.
research In brief
Pilomatricomas don't follow the usual hair follicle cell differentiation process.
research Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA ‐1 expression
Matrical tumors share a common growth mechanism involving the Wnt pathway and consistent PHLDA1 expression.
research Trachyonychia with juvenile pityriasis rubra pilaris
A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
research Trichothiodystrophy hair shafts display distinct ultrastructural features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research Keratins and disease at a glance
Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
research Animal models of human skin disease
Mutations in certain skin proteins cause severe skin issues, while others have limited effects, highlighting the need to understand these proteins for better treatments.
research Epidermal Differentiation Enhances CRABP II Expression in Human Skin
research Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis
CXCR2 in skin cells promotes tumor growth.
research The RAIG Family Member, GPRC5D, Is Associated with Hard-Keratinized Structures
GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
research Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis
Deleting a specific protein in skin cells disrupts normal hair growth and development.
research Architecture of Reconstructed Epidermis on Collagen Lattices Varies according to the Method Used: A Comparative Study
The method and source of keratinocytes affect the structure of reconstructed skin.
research Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia
Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.
research Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles
research Hypotrichosis and nail dysplasia: A novel hidrotic ectodermal dysplasia
A 3-year-old girl has a rare condition causing sparse hair and nail issues, with minimal improvement from treatment.
research Hair Keratins and Hair Follicle–Specific Epithelial Keratins
Hair and follicle keratins differ in structure and expression, especially in cysteine content.
research Intercellular junctions in normal epidermis
Desmosomal adhesion is essential for healthy skin structure and function.