research Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
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research Treatment of androgen excess in females: Yesterday, today and tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research AN ATTEMPT TO ASSESS THE MAGNITUDE OF ENDOGENOUS ANDROGEN PRODUCTION IN A CASE OF THE ADRENOGENITAL SYNDROME*
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Lack of endocrine systemic side effects after topical application of spironolactone in man
Topical spironolactone cream doesn't cause hormone-related side effects in the body.
research Mechanism of Cuticle Hole Development in Human Hair Due to UV-Radiation Exposure
UV radiation damages hair by creating holes and peeling cuticle layers.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research The role of androgens in hormone replacement therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Anti-androgen therapy in dermatology: a review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Telogen Effluvium
Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
research Steroid Hormones
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Influence of Saw palmetto and Pygeum africana extracts on the urinary concentrations of endogenous anabolic steroids: Relevance to doping analysis
Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.
research Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression
Depressed teens have different steroid levels in urine, which may help identify and treat them.
research Monocyclic Aromatic Compounds
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research Traditional Knowledge Digital Library: The Challenges Ahead
The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.
research Ursolic acid, a pentacyclic triterpene from Ochrosia elliptica Labill leaves and its role in the management of polycystic ovary syndrome (PCOS)
Ursolic acid from Ochrosia elliptica leaves may help manage PCOS symptoms.
research Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin- induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress
Krill oil may help reduce prostate enlargement and growth.
research A Multidimensional Study Integrating Traditional Chinese Medicine and Network Pharmacology: Exploring the Skin Repair and Anti-Aging Effects of a Specific Combination of Five-Colored Plants
The plant combination effectively repairs skin and delays aging.
research Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies
Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.
research Deciphering of Anti-Alopecia Activity of Polyphenol from Beta vulgaris Root against 5α-reductase: Molecular Insight
Beetroot extract may help treat hair loss naturally with fewer side effects.
research Understanding Polycystic Ovary Syndrome
PCOS affects women's hormones and metabolism, but can be managed with lifestyle changes and treatments.
research Selected abstracts from the 47th meeting of the Irish Endocrine Society Sligo, 24th & 25th November 2023
Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.
research Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
Removing SIX1 in fat cells reduces skin fibrosis.
research Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Subject Index
research Hair regeneration by small molecules that activate autophagy
Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
research Systemic Antifungals
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Poster Abstracts
The model and estimator can predict drug exposure in kidney transplant patients well.