53 citations
,
September 2013 in “Journal of Investigative Dermatology” Hair follicle cells help protect against immune attacks by regulating T-cell activity.
53 citations
,
May 2011 in “Dermatologic therapy” Alopecia areata is a skin condition causing hair loss, and its exact cause is unknown, but it may involve biological mechanisms.
50 citations
,
May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
50 citations
,
July 2015 in “Journal of the American Academy of Dermatology” Using 2.5 mg/mL triamcinolone acetonide is effective for hair growth in alopecia areata with fewer side effects.
48 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Contact sensitizers like DCP and SADBE are the most effective treatments for alopecia areata.
47 citations
,
April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
46 citations
,
July 2008 in “Dermatologic Therapy” A scale was made to measure hair loss severity in African American women.
44 citations
,
January 2021 in “Dermatologic Therapy” COVID-19 may cause hair loss due to infection stress or treatments.
42 citations
,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
41 citations
,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
41 citations
,
February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
40 citations
,
July 2017 in “Frontiers in Medicine” Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
38 citations
,
September 2004 in “Journal of Autoimmunity” Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.
37 citations
,
December 1995 in “Journal of Cell Science” Nexin 1 may help control hair growth.
36 citations
,
August 2021 in “Nature Cell Biology” Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
36 citations
,
July 2017 in “Journal of controlled release” A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
36 citations
,
June 2012 in “PubMed” There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
36 citations
,
March 2009 in “Molecular Carcinogenesis” Disrupting Bcl-xL in mice reduces skin cancer risk.
35 citations
,
June 2018 in “Urology” The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
35 citations
,
July 2008 in “Dermatologic therapy” Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.
32 citations
,
March 2008 in “SKINmed Dermatology for the Clinician” Accurate diagnosis and tailored treatment are crucial for managing complex hair loss conditions.
31 citations
,
March 2009 in “Archives of Facial Plastic Surgery” The hairline-lowering surgery was effective, safe, and left patients satisfied with few complications.
31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
31 citations
,
October 2002 in “Journal of Investigative Dermatology” IL-10 may worsen alopecia areata instead of helping it.
30 citations
,
October 2013 in “Lupus” Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
29 citations
,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
28 citations
,
January 2015 in “Journal of Cell Science” PINCH-1 is crucial for skin cell adhesion and movement, working with EPLIN and ILK.