January 2025 in “RSC Pharmaceutics” Smart microneedles using advanced tech could improve psoriasis treatment.
July 2018 in “Elsevier eBooks” Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
23 citations
,
June 2015 in “Oncology Letters” Adipose-derived stem cell-conditioned medium can reduce melanoma cell growth and spread.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
195 citations
,
January 2008 in “Photochemistry and Photobiology” Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
179 citations
,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
165 citations
,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
163 citations
,
April 2019 in “Nature Communications” Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
97 citations
,
September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
96 citations
,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
87 citations
,
July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
65 citations
,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
63 citations
,
May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
62 citations
,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
59 citations
,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
32 citations
,
August 2019 in “Nature Communications” Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
6 citations
,
January 2023 in “npj regenerative medicine” Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
5 citations
,
October 2024 in “International Journal of Biological Sciences” A peptide from hair follicle stem cells can boost hair growth.
5 citations
,
January 2017 in “Laboratory Animal Research” Gold thread implantation may help hair grow in humans and mice.
4 citations
,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
The treatment was ineffective in humans.
January 2023 in “Annali di stomatologia” PRP helps heal and repair tissues in medicine but needs more research for better use.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.
1039 citations
,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
260 citations
,
June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
256 citations
,
October 2013 in “Nature Communications” Bioengineered lacrimal glands can restore tear production and protect eyes.