research Hair toxic and essential trace elements in children with autism spectrum disorder
Children with autism have lower levels of essential and toxic trace elements in their hair.
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research Efficacy and safety of the Exfoliate-Dissolve-Repair skin care approach in the treatment of keratosis pilaris: a randomized controlled clinical trial study protocol
The Exfoliate-Dissolve-Repair skincare approach may effectively treat keratosis pilaris and reduce the need for corticosteroids.
research Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome
Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
research Complementary, Holistic, and Integrative Medicine: Eating Disorders
Some alternative therapies might help treat eating disorders when combined with standard care, but more research is needed to confirm their safety and effectiveness.
research Disorders of Keratinization
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
research Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review
Exposure to toxic elements like mercury and lead may be linked to autism, and a higher zinc to copper ratio might help protect against it.
research The psychosocial impacts of vitiligo, psoriasis, and alopecia areata on pediatric patients
Kids with vitiligo, psoriasis, or alopecia areata are more likely to experience anxiety, depression, and social challenges.
research The effectiveness of remote interventions based on digital health technology in kidney transplant recipients: a systematic review
Digital health technology improves health and medication adherence in kidney transplant patients.
research Case 1: Intractable Rash in a 7-month-old Boy
The baby's rash and hair loss were cured with zinc supplements and better skin care.
research A Systematic Literature Review of Alopecia Areata in Children and Adolescents: Psychosocial Impact
Alopecia areata negatively affects self-esteem, relationships, and academics in young people.
research Transient heart failure in an adult with kawasaki disease
An adult with Kawasaki disease experienced temporary heart failure but recovered without lasting heart damage.
research A rare case of Vitamin D dependent rickets type II: a case report
A child with a rare type of rickets showed some improvement with high doses of vitamin D, but such conditions often respond poorly to treatment.
research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing
CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
research DENOUEMENT—CONTINUED FROM P. 661
Tinea faciei should be considered in neonatal vesicular lesions and confirmed with KOH examination and culture.
research Involvement of Weibel-Palade bodies in Kaposiform haemangioendothelioma
Combining hair transplantation with PRP is more effective for treating hair loss than hair transplantation alone.
research Focal palmoplantar callosities in non-Herlitz junctional epidermolysis bullosa
Focal palmoplantar callosities may help diagnose non-Herlitz junctional epidermolysis bullosa.
research Contents
The document summarizes recent dermatological treatments and advances in areas like pediatric care, wound healing, skin closure, light-based therapies, pigment disorders, hair loss, immunotherapy, infection management, melanoma, drug reactions, and facial rejuvenation.
research Common Dermatologic Disorders in Down Syndrome: Systematic Review (Preprint)
People with Down syndrome have a higher risk of skin disorders and need better screening and treatment.
research 128 Bimekizumab led to rapid & deep normalisation of molecular signatures associated with PASI sub-components, preceding clinical skin clearance
The study investigated the effects of bimekizumab (BKZ) on psoriatic skin, focusing on the Psoriasis Area and Severity Index (PASI) sub-components: erythema, thickness, and scaling. In the BE RADIANT trial, patients receiving BKZ showed significant reductions in these sub-scores by Week 8, with ≥95% improvement by Week 12, maintained through Week 48. Molecular analysis revealed complete normalization of gene signatures associated with these sub-components by Week 8. The study found a correlation between changes in interleukin (IL)17A/IL17F expression and gene expression changes, highlighting BKZ's impact on keratinocytes. The results demonstrate that molecular resolution precedes clinical skin clearance, with all sub-components being reliable indicators of BKZ response.
research Clinical case of alopecia totalis in pediatric practice
An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
research Systemic minoxidil for hair disorders in pediatric patients: a safety and tolerability review
Low-dose oral and sublingual minoxidil seem safe for children with hair disorders.
research Pityriasis versicolor on the scalp: An unusual distribution of a common disease
A boy's scalp infection, usually found on the body, was effectively treated with antifungal cream.
research KERATINS AND SKIN DISORDERS
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Shushing down the epigenetic landscape towards stem cell differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research Reviewing and Exploring the Prospects of Platelet-Rich Plasma (PRP) Therapy in the Context of Pediatric Surgical Wound Management
PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
research Precocious puberty in a 24 month old Nigerian girl: case report
A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.
research Searching for a Lead: Diagnosing a Rare Cause of Recurrent Intussusception
A trichobezoar caused the girl's recurrent intussusception, and surgery plus psychiatric therapy resolved her symptoms.
research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
research Direct‐to‐consumer healthcare and its expanding role in the Australian healthcare system
Direct-to-consumer telemedicine in Australia needs formal evaluation for safety and quality.
research Investigation of parental socioeconomic status as a determinant of dietary habits and disease severity of sickle cell disease children
Parental socioeconomic status doesn't improve dietary habits or reduce disease severity in children with sickle cell disease.