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March 2006 in “Journal of Medical Genetics” A mutation in the KRTHB5 gene causes hair and nail issues.
35 citations
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September 2006 in “American Journal Of Pathology” Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.
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January 2018 in “PubMed” Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.
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November 1969 in “Journal of Investigative Dermatology” A new staining method clearly shows nerves around eyebrow hair follicles.
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February 2015 in “Experimental Dermatology” Keratins are crucial for hair strength, and mutations in certain keratin genes cause hair disorders.
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July 2021 in “Life science alliance” PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.
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November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
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April 2000 in “Mammalian Genome” A new mutation in mice causes crooked whiskers and messy hair.
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March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
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June 2018 in “Cryobiology” Freezing nitrogen ethanol composite is safer than liquid nitrogen for treating musculoskeletal tumors.
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July 1988 in “PubMed” Rhino mice show significant meibomian gland changes, making them a potential model for studying gland disorders.
June 1997 in “Australasian Journal of Dermatology” Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.
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January 2004 in “Elsevier eBooks” 11 citations
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November 1998 in “Journal of dermatological science” Knocking out certain genes in mice helps understand skin and hair growth problems.
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February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Keratin films from human hair can potentially replace human nail plates for drug testing.
January 2024 in “Journal of Cutaneous and Aesthetic Surgery” The modified needle is safer for procedures by reducing injury risk.
October 2021 in “Journal of Investigative Dermatology” Dkk4 protein is necessary for the proper development and arrangement of hair follicles.
January 2014 in “Pathology” Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
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May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
Retinoids can help reduce keratin buildup in skin conditions.
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December 1988 in “Differentiation” Trichocytic differentiation starts in cells with epithelial cytokeratins, transitioning to trichocytic cytokeratins in hair and gradually in nails.
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March 2016 in “Journal of the European Academy of Dermatology and Venereology” Almost all patients with chronic kidney disease not yet on dialysis have at least one skin problem.
March 2026 in “Scholars Journal of Medical Case Reports” Nail issues are common in kids with alopecia areata and should be checked for better diagnosis.
January 2025 in “Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
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January 2024 in “European Journal of Case Reports in Internal Medicine” Beau's lines on fingernails might indicate past severe COVID-19 and risk of reinfection.
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January 2022 in “Medical Mycology Journal” Malassezia fungi in healthy noses can form a "spaghetti-and-meatballs" structure.
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March 2013 in “Biology Letters” Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.
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November 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cystatin M/E helps in the final stages of hair and nail formation by controlling certain enzymes.