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Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

research Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

9 citations , April 2019 in “International Journal of Molecular Sciences”

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture

6 citations , October 2020 in “Journal of Cellular and Molecular Medicine”

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress

2 citations , January 2023 in “International journal of biological sciences”

Gray hair can potentially be reversed, leading to new treatments.

Integrative Whole-Transcriptome Sequencing Analysis of Skin Tissues with Different Coat Types in Cashmere Goats Across Stages of Hair Follicle Development

research Integrative Whole-Transcriptome Sequencing Analysis of Skin Tissues with Different Coat Types in Cashmere Goats Across Stages of Hair Follicle Development

January 2026

The study found that different genes are active in cashmere goats' hair growth stages, which can help improve cashmere production.

research Assessment of adipokines, hormonal profile, lipid profile, and insulin resistance in patients with androgenetic alopecia

January 2026 in “Egyptian Journal of Dermatology and Venerology”

Androgenetic alopecia is linked to insulin resistance and hormonal imbalances.

A Prospective, Randomized Double-Blind, Placebo-Controlled Study for Safety and Efficacy of SesZen-Bio: A Proprietary Sesbania Grandiflora Extract in Managing Hair and Scalp Health in Healthy Adults

research A prospective, randomized double-blind, placebo-controlled study for safety and efficacy of SesZen-BioTM: a proprietary Sesbania grandiflora extract in managing hair and scalp health in healthy adults

April 2024 in “International journal of clinical trials”

SesZen-Bio™ improves hair density, thickness, and overall hair health.

research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies

August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

research Formulation, Selection, Physical Properties and Antifungal Effect Evaluation of Semi-solid Dosage Forms with Organic Acids

April 2026 in “Lithuanian University of Health Sciences”

Cinnamic acid in hydrogels can effectively fight fungi but spreads less than in solution.

Natural Product-Inspired Bis(Trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies

research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies

August 2025 in “ACS Omega”

New compounds show promise as nonsteroidal treatments for hair loss.

Physical Stability Test of Hair Tonic with Cinnamon Essential Oil and Virgin Coconut Oil Using Cycling Test Method and Irritation Test on Rabbits

research PHYSICAL STABILITY TEST HAIR TONIC COMBINATION Cinnamon (Cinnamomum burmanii) ESSENTIAL OIL AND VCO (VIRGIN COCONUT OIL) WITH CYCLING TEST METHOD AND IRRITATION TEST ON THE RABBIT

May 2023 in “Jurnal farmasi sains dan praktis”

The hair tonic with cinnamon oil and coconut oil was stable and caused very mild irritation.

research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol

16 citations , August 2004 in “Tetrahedron”

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

research 519 Design of a new molecule proven to be safe and effective for topical depigmenting and antiaging method

November 2022 in “Journal of Investigative Dermatology”

A new molecule was found to be a safe and effective skin lightener and anti-aging product.

research Clobetasol/minoxidil

February 2023 in “Reactions Weekly”

research Ketoconazole-p Aminobenzoic Cocrystal Exhibits a Potent Anti-inflammatory Effect on the Skin of BALBc Mice

April 2021 in “Research Square (Research Square)”

The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.

research Cyclooxygenases in the skin: pharmacological and toxicological implications

165 citations , September 2003 in “Toxicology and applied pharmacology”

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

research Diphlorethohydroxycarmalol, Isolated from Ishige okamurae, Increases Prostaglandin E₂through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

9 citations , November 2012 in “Biomolecules & therapeutics”

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

research Comparative evaluation for the efficacy and tolerance of two skin products containing either hydroquinone or emblica extract with kojic acid in female subjects with facial dyschromia

February 2009 in “Journal of the American Academy of Dermatology”

Both skin products were equally effective in improving facial discoloration and skin quality.

research
Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats

46 citations , April 2020 in “Clinical Cosmetic and Investigational Dermatology”

Hydroquinone may harm skin, while kojic acid and aloe vera could reduce its negative effects.

research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1

28 citations , September 2000 in “Journal of Medicinal Chemistry”

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

research Clinical Snippets

1 citations , March 2003 in “Journal of Investigative Dermatology”

Early sunburn treatment with certain inhibitors may reduce skin cancer risk.

research
Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation

45 citations , March 2020 in “International Journal of Nanomedicine”

Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.

research Downregulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors

May 2004 in “International Journal of Cosmetic Science”

Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.

research Penggunaan Simplex Lattice Design (SLD) dalam Optimasi HPMC dan Propilen Glikol Formula Gel Cinchonine Sebagai antibakteri Cutibacterium acnes (C.Acne)

June 2025 in “Healthy-Mu Journal”

The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.

Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum Japonicum: Glycosylation of Methyl Gallate with Ulosyl Bromides

research Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum japonicum : Glycosylation of Methyl Gallate with Ulosyl Bromides

June 2025 in “Natural Product Communications”

Researchers created 10 new compounds similar to cercidin, which could lead to new antibiotics.

research Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery

15 citations , February 2014 in “Toxicology Letters”

Coumarin derivatives cause skin irritation, but coumarin itself does not.

research In Vivo Evaluation of Cromolyn Sodium Topical Gels for the Treatment of Atopic Dermatitis

April 2025 in “Digital Commons - East Tennessee State University (East Tennessee State University)”

Cromolyn sodium oleate gel is more effective and safer for treating atopic dermatitis than dexamethasone.

Niosomal Versus Cubosomal Gels of Cetirizine Hydrochloride: Cost-Effective Permeation Enhancement for Potential Transdermal Application

research Niosomal versus cubosomal gels of cetirizine hydrochloride: Cost-effective permeation enhancement for potential transdermal application

October 2025 in “Pharmaceutical Development and Technology”

Cubosomal gels enhance skin absorption of cetirizine better than niosomal gels.

Nano-Spanlastics-Loaded Dissolving Microneedle Patches for Ketotifen Fumarate: Advanced Strategies for Allergic Conjunctivitis Treatment and Molecular Insights

research Nano-spanlastics-loaded dissolving microneedle patches for ketotifen fumarate: advanced strategies for allergic conjunctivitis treatment and molecular insights

18 citations , February 2025 in “Drug Delivery and Translational Research”

The microneedle patches effectively treat allergic conjunctivitis with controlled, sustained release of medication.

research Novel Quinazoline Derivative Induces Differentiation of Keratinocytes and Enhances Skin Barrier Functions against Th2 Cytokine-Mediated Signaling

2 citations , August 2023 in “Molecules”

SH-340 may improve skin barrier and help treat atopic dermatitis.

research Dyeing behaviours of amino heterocyclic compounds as blue oxidative hair dye precursors applied to keratin fibres

5 citations , January 2011 in “International Journal of Cosmetic Science”

1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.