research Autoimmune skin disease pathogenesis: a chronological immune cascade and multi-hit model
Autoimmune skin diseases result from genetic and environmental factors disrupting immune checkpoints.
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540-570 / 1000+ results research A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice.
CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
research Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Supplementary figure S2
research Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermisin vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
research Organization of microfibrils in keratin fibers studied by X-ray scattering
The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
research P.6.028 Transnosography of impulsiveness:A comparison among different psychiatric disorders
Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.
research Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016–2023)
Myhre syndrome symptoms worsen over time, with specific genetic variants affecting severity.
research A sport crisis typology: establishing a pathway for future research
The document concludes that future research should focus on tailored solutions for managing sports crises and consider legal and cultural factors.
research The relationship between stress resistance and psychological well-being of counseling psychologists
Improving stress resistance can boost the well-being of counseling psychologists.
research Assessment of Multidimensional Health Care Parameters Among Adults in Japan for Developing a Virtual Human Generative Model: Protocol for a Cross-sectional Study (Preprint)
The study aims to create a model to improve personalized and preventive health care.
research 591 A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Multi-scale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research 1344 Novel human 3D skin model for skin aging research
Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
research Genetic correlation by pedigree analysis in patients diagnosed with PCOS as per Rotterdam’s criteria
PCOS is likely inherited in families, increasing risk for first-degree relatives.
research Molecular Mechanisms in the Etiology of Polycystic Ovary Syndrome (PCOS): A Multifaceted Hypothesis Towards the Disease with Potential Therapeutics
research Structural changes in trichocyte keratin intermediate filaments during keratinization
Keratin structure changes during keratinization, but the exact model remains uncertain.
research Cutaneous neuroimmunology – lessons from the hair follicle
Stress and certain chemicals affect hair growth by interacting with the immune and nervous systems.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Induction of dark keratinocytes by 12-O-tetradecanoyl-phorbol-13-acetate and mezerein as an indicator of tumor-promoting efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Before & beyond the pain – Allostatic load, central sensitivity and their role in health and function
Recognizing and managing central sensitization and stress is crucial for treating chronic pain.
research Mindfulness and Its Predictors in Women With Polycystic Ovary Syndrome
Demographic factors like age, education, and marriage duration affect mindfulness in women with PCOS.
research Mitogen‐regulated protein/proliferin mRNA induction following single applications of tumor promoters to murine skin
mrp/plf-mRNA can indicate tumor-promoting effects in skin.
research A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response
A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.
research Abnormalities of Purkinje Cell Arborization in Brindled Mouse Cerebellum
Cupric chloride treatment corrected abnormal Purkinje cell development in brindled mice.
research Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior
Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
research Parsing patterns: Emerging roles of tissue self-organization in health and disease
Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.