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As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Desmosomes are crucial for skin and heart development, and JNK may help regulate them.

Human keratinocytes do not naturally respond to androgens.

The new model helps understand and develop treatments for genetic skin disorders like AEC.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

A new type of pachyonychia congenita may exist, caused by a different keratin mutation.

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

Human hair keratin genes hHa2 and hHb1 are located on chromosomes 17 and 12.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Atoh1 expression can create new Merkel cells in the skin.

A specific gene mutation causes a severe skin disorder in a family.

A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.

RAR-gamma 1 is important for normal skin maintenance and differentiation.

A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.

The KRTAP13-3 gene affects wool fibre diameter variability in Chinese Tan sheep.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

The study found 65 intermediate filament genes, including new keratins, and suggested updating keratin naming.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

CTHRC1 helps sweat glands recover by rebuilding nearby blood vessels.

Mrp3 helps in wound healing and hair growth.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

K42 and K124 keratins are only found in horse hoof lamellae.

The KAP13-3 gene in sheep affects wool quality by influencing keratin assembly.

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.