72 citations
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August 2014 in “Genome Biology and Evolution” Feather diversity is due to different keratin gene combinations, and chickens can help study human keratin diseases.
47 citations
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January 2024 in “iScience” Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
35 citations
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January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
22 citations
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March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
19 citations
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March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
15 citations
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July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
14 citations
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February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
9 citations
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June 2024 in “Cell Reports” Hair follicles play a crucial role in regulating skin barrier function.
8 citations
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June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
1 citations
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August 2023 in “Journal of cutaneous pathology” The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
September 2025 in “Animal Bioscience” Key genes and pathways affect wool fiber thickness, improving wool quality.
A genetic variant in the KRT71 gene may cause loose anagen hair and wooly hair, and symptoms might improve with age.
March 2025 in “International Journal of Trichology” Oral minoxidil improved hair thickness in a person with monilethrix.
February 2025 in “BMC Veterinary Research” Keratin proteins are crucial for hair growth in cashmere goats.
November 2024 in “Journal of Functional Foods” AP collagen peptides improve hair elasticity and gloss.
March 2023 in “International journal of trichology” Six genetic conditions are often linked to complete scalp hair loss in children.
Understanding genetics is crucial for treating heart and skin diseases.
April 2017 in “Journal of Investigative Dermatology” The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.
10 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
96 citations
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June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
October 2024 in “BMC Genomics” Understanding hair follicle development can help improve cashmere quality.
2 citations
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July 2021 in “Genes” A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
February 2022 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Hair shaft disorders, often due to genetics or environment, lack specific treatments but can be managed with gentle hair care and may improve with age or topical treatments.
85 citations
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January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
65 citations
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December 2015 in “Experimental dermatology” Corticosteroid treatment reduces inflammation and alters hair keratins in alopecia areata.
26 citations
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January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
24 citations
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May 2022 in “BMC Veterinary Research” lncRNAs play a key role in hair follicle development, affecting cashmere quality and yield.
21 citations
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January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
19 citations
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December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.