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research Latent transforming growth factor beta-binding protein 1 (LTBP1): roles as a multifunctional extracellular matrix regulator in human disease. From molecular mechanisms to clinical translation prospects

March 2026 in “Folia Histochemica et Cytobiologica”

LTBP1 is a key regulator in diseases and a potential target for new treatments.

research Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing

99 citations , October 2008 in “Journal of Investigative Dermatology”

Mutations in the ST14 gene cause skin and hair issues by disrupting important protein processing.

research New case of trichorinophalangeal syndrome-like phenotype with a de novo t(2;8)(p16.1;q23.3) translocation which does not disrupt the TRPS1 gene

9 citations , May 2014 in “BMC medical genetics”

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

research IMUNOLOKALISASI EPIDERMAL GROWTH FACTOR (EGF) PADA LUKA BAKAR TIKUS PUTIH (RATTUS NORVEGICUS) YANG DIINDUKSI EKSTRAK MEDIA PENUMBUH SEL PUNCA MESENKIMAL (EMPSPM)

January 2016

MSC-CM cream speeds up burn wound healing better than the control treatment.

research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells

31 citations , October 2010 in “BMB Reports”

L-threonate may help prevent balding by blocking a key protein.

research Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis

100 citations , May 2006 in “American Journal Of Pathology”

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

research Class III Peroxidases PRX01, PRX44, and PRX73 Control Root Hair Growth in Arabidopsis thaliana

19 citations , May 2022 in “International journal of molecular sciences”

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

research Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles

30 citations , February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Plet-1 protein helps hair follicle cells move and stick to tissues.

research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

109 citations , November 2011 in “Nature Neuroscience”

Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research No evidence for THAP1/DYT6 variants as disease modifiers in DYT1 dystonia

10 citations , June 2011 in “Movement Disorders”

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

research Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles

40 citations , March 1991 in “Journal of Investigative Dermatology”

research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation

79 citations , August 1998 in “The Journal of Cell Biology”

Keratin 16 delays skin maturation and affects skin and hair development in mice.

research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End ofKRT10

22 citations , September 2014 in “JAMA dermatology”

Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.

research Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes

90 citations , February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Interleukin-1 increases keratin K6 production in skin cells.

research The Serine Protease Activity of Corin Is Required for Normal Pigment Type Switching

8 citations , August 2018 in “Journal of Investigative Dermatology”

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

60 citations , November 2013 in “Development”

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene on Fiber Traits in Inner Mongolia Cashmere Goats

research Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene on Fibre Traits in Inner Mongolia Cashmere Goats

20 citations , May 2007 in “Asian-Australasian Journal of Animal Sciences”

KAP8.2 gene variations affect cashmere quality in goats.

research Hydrolyzed Hair Keratin

January 2007

research A pan-European register-based observational study of abrocitinib and conventional systemic therapies in moderate and severe atopic dermatitis: the DREAM TO TREAT AD study protocol

1 citations , April 2025 in “Skin Health and Disease”

Abrocitinib is being evaluated for safety and effectiveness in treating moderate to severe atopic dermatitis.

research Distribution of caspase‐14 in epidermis and hair follicles is evolutionarily conserved among mammals

21 citations , September 2005 in “The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology/Anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology”

Caspase-14 is important for skin and hair development in all mammals.

research The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation

24 citations , March 2016 in “Journal of Investigative Dermatology”

TIP39 and PTH2R help control calcium levels and skin cell development.

research Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin

10 citations , November 2018 in “Genetics in medicine”

Lack of cystatin M/E causes thin hair and dry skin.

research Cytokeratins as Markers of Follicular Differentiation

121 citations , December 2001 in “American Journal of Dermatopathology”

TB and BCC tumors show similar follicular differentiation patterns.

research Bio‐active designed peptide for hair keratin strengthening

March 2026 in “International Journal of Cosmetic Science”

Pal-KCV peptide strengthens hair and reduces breakage by up to 52%.

research Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in nackt Mice, a Cathepsin L-Deficient Mutation

57 citations , August 2002 in “American Journal Of Pathology”

Cathepsin L deficiency causes hair and skin issues in mice.

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