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Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

research Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice

7 citations , February 2023 in “Inflammation and Regeneration”

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

research NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor

91 citations , December 2019 in “The EMBO Journal”

NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.

research Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations

115 citations , October 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

research Trichohyalin: A structural protein of hair, tongue, nail, and epidermis

27 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

research Regulatory role of LEF-1 in the proliferation of Arbas White Cashmere goat dermal papilla cells

9 citations , April 2018 in “Canadian Journal of Animal Science”

LEF-1 boosts cell growth in goat hair follicles, aiding cashmere production.

research Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2

55 citations , June 2014 in “Nature Communications”

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

research Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions

7 citations , March 2023 in “The Journal of Biochemistry”

LONRF1 is important for oxidative damage response and tissue remodeling during wound healing.

research Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes

79 citations , January 2002 in “Nucleic Acids Research”

BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.

research Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair

28 citations , December 2008 in “Laboratory investigation”

Activin activation in skin cells speeds up wound healing without affecting scar quality.

research Pannexin 3 regulates skin development via Epiprofin

13 citations , January 2021 in “Scientific Reports”

Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.

research The roles of activins in repair processes of the skin and the brain

52 citations , July 2001 in “Molecular and cellular endocrinology”

Activin A helps heal skin wounds and protects the brain after injury.

research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

2 citations , January 1993

Trichohyalin is a versatile protein involved in hair and skin structure.

research Effects of lncRNA MTC on protein expression in skin fibroblasts of Liaoning Cashmere goat based on iTRAQ technique

January 2022 in “Figshare”

lncRNA MTC helps goat skin cells grow and may aid hair growth by controlling proteins linked to cell growth.

research Alkaline Phosphatase–Regulated C–C Motif Chemokine Ligand 5 (CCL5) Functions as a Critical Mediator of Hair Follicle Neogenesis

March 2026 in “Tissue Engineering and Regenerative Medicine”

research Types I and II Keratin Intermediate Filaments

211 citations , April 2018 in “Cold Spring Harbor Perspectives in Biology”

Keratins are crucial for cell structure, growth, and disease risk.

research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?

30 citations , August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

TGase 3 helps build hair structure by forming strong bonds between proteins.

research The Molecular Architecture for the Intermediate Filaments of Hardα-Keratin Based on the Superlattice Data Obtained from a Study of Mammals Using Synchrotron Fibre Diffraction

7 citations , January 2011 in “Biochemistry Research International”

Hard α-keratin has a universal molecular structure with a specific superlattice arrangement.

research Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells

1 citations , January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Weak cell junctions disrupt hair follicle stem cell rest.

research Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction

182 citations , June 2017 in “Biomaterials”

Special fiber materials boost the healing properties of certain stem cells.

research TNF superfamily in skin appendage development

86 citations , May 2008 in “Cytokine & growth factor reviews”

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

research RETRACTED ARTICLE: Up-regulated lncRNA5322 elevates MAPK1 to enhance proliferation of hair follicle stem cells as a ceRNA of microRNA-19b-3p

9 citations , June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

research Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray

4 citations , September 2016 in “Molecular Medicine Reports”

Specific genes influence hair and cashmere growth in Laiwu black goats.

research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins

13 citations , January 2018 in “Advances in experimental medicine and biology”

Comparison of Mesenchymal Progenitor Cell Coating on MBA and DBM as Biochemical Scaffolds

research The comparison of the mesenchymal progenitor cell coating state on the MBA and DBM as the biochemical scaffolds

September 2011 in “Clinical Biochemistry”

The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.

research 573 Biomarkers quantifying changes in the hair follicular extracellular matrix are elevated in patients with alopecia

November 2024 in “Journal of Investigative Dermatology”

Changes in hair follicle structure may help diagnose and monitor alopecia.

research Expression of Signaling Components in Embryonic Eyelid Epithelium

5 citations , February 2014 in “PloS one”

Eyelid cells share signaling components but differ in pathway activity.

research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche

3 citations , December 2024 in “Stem Cell Reports”

Low fucosylation boosts stem cell growth in the eye.

research Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins

33 citations , October 2012 in “Journal of Morphology”

Reptile skin hardens by layering beta-proteins on keratin.

research Apoptosis and keratin intermediate filaments

180 citations , April 2002 in “Cell Death and Differentiation”

research Assembly of Hair Keratins in Transfected Epithelial Cells

5 citations , December 1996 in “Biochemical and Biophysical Research Communications”

Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.

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