research 3D multicellular micropatterning biomaterials for hair regeneration and vascularization
The new biomaterial helps grow blood vessels and hair for skin repair.
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research Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro
Basement membrane-like ECM supports fibroblast aggregation and cohesion.
research The art of process chemistry
research HtrA1L364P leads to cognitive dysfunction and vascular destruction through TGF‐β/Smad signaling pathway in CARASIL model mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
research From structural resilience to cell specification — Intermediate filaments as regulators of cell fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research Lichen planus pigmentosus and lichen planopilaris
Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
research 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation
Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
research Visualization of individual cell division history in complex tissues
The tool iCOUNT helps understand how stem cells divide and affect tissue development and repair.
research 891 Comparison of phenotypes and transcriptomes of mouse skin-derived precursors and dermal mesenchymal stem cells
The search scheme SMRI is faster and more secure for retrieving encrypted data from the cloud.
research Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research DEEP REINFORCEMENT LEARNING FOR SCALABLE CONTROL OF BOOLEAN MODELS IN THE CONTEXT OF CELLULAR REPROGRAMMING
pbn-STAC effectively finds strategies for cellular reprogramming using deep reinforcement learning.
research Potassium channel conductance as a control mechanism in hair follicles
research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte
The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.
research The Follicular Automaton Model: Effect of Stochasticity and of Synchronization of Hair Cycles
The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
research Mitochondrial Dysfunction in Lichen Planopilaris with Focus on Oxidative Stress and Metabolic Reprogramming
Mitochondrial dysfunction and oxidative stress may play a role in Lichen Planopilaris.
research The organization of the keratin I and II gene clusters in placental mammals and marsupials show a striking similarity
Keratin gene clusters in humans and marsupials are similarly organized.
research Diversity of human skin three-dimensional organotypic cultures
research Pattern Formation
The conclusion is that understanding how patterns form in biology is crucial for advancing research and medical science.
research Unexpectedly high carrier rates and genotype/phenotype correlation; LIPH mutations in Japanese autosomal recessive woolly hair/hypotrichosis
Certain gene mutations in Japanese people are linked to different types of hair loss, with some causing mild hair thinning and others leading to complete baldness.
research Sculpting with stiffness: rigidity as a regulator of morphogenesis
Tissue stiffness helps shape how organisms develop.
research Attraction of sensory fibers by Merkel cells during co-culture of sensory ganglia and hair follcies in collagen-gel
research Structural Stability of Wild Type and Mutated α-Keratin Fragments: Molecular Dynamics and Free Energy Calculations
The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.
research The stiffness of the extracellular matrix is a key factor in tumor progression
Extracellular matrix stiffness affects how aggressively cancer cells invade.
research 564 Subpopulations of dermal fibroblasts produce distinct extracellular matrices
Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
research Transglutaminase-mediated cross-linking in mammalian epidermis
research ‘Follicular Swiss cheese’ pattern - another histopathologic clue to alopecia areata
Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
research Msx2 Prevents Stratified Squamous Epithelium Formation in the Enamel Organ
Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.
research Dense Packing
Dense packing fits many hair grafts closely together for a natural look but isn't suitable for everyone.
research STUDY ON CONNECTIVE TISSUE FIBRE IN NECK SKIN OF GOAT
Goat neck skin has a complex network of collagen, elastic, and reticular fibers.