research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
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30 / 1000+ results research LC‐MS/MS‐based method for long‐term steroid profiling in human scalp hair
research Determination of cortisone and cortisol in human scalp hair using an improved LC-MS/MS-based method
Cortisone in hair is a more reliable indicator of stress hormone exposure than cortisol.
research Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays
The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.
research Total testosterone to dihydrotestosterone ratio assessed by LC-MS/MS predicts a worse metabolic profile not only in PCOS patients
A higher testosterone to dihydrotestosterone ratio may indicate worse metabolic health in women.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research LC-MS/MS improves screening towards 21-hydroxylase deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research Simultaneous LC-MS/MS quantification of glucocorticoids, melatonin and its metabolites in hair
The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
research Quantitative analysis of 34 sex (pro)hormones, conjugates and bioactive oxidation products thereof in human plasma by GC- and LC-MS/MS and systematic investigation of overestimations of analyte concentrations not accounted for by method validation
The method accurately measures sex hormones in human plasma but can have small errors.
research Matrix matching in quantitative bioanalysis by LC–MS/MS a dream or a reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure
Diet and sunlight are important for maintaining good vitamin D levels.
research The impact of COVID-19 pandemic and lockdown on chronic stress assessed by hair cortisol analysis via LC-MS/MS
Chronic stress increased after lockdown, especially in young adults and females.
research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS
A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
research LC-MS/MS-based reference intervals for hair cortisol in healthy children
Hair cortisol levels change with age, starting high at birth, decreasing until age 6, then rising to adult levels by age 18.
research SUN-195 Falsely Elevated Testosterone Levels: Role of LC-MS/MS in Reducing Unnecessary Testing
Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
research Bioequivalence of finasteride tablet in healthy volunteers by LC-MS/MS
The two finasteride tablets are bioequivalent.
research Determination of Exemestane in Human Plasma by LC-MS-MS
The method effectively showed that the two exemestane preparations are bioequivalent.
research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics
The method accurately measures finasteride in plasma and is suitable for clinical use.
research Stability Study of Finasteride: Stability-Indicating LC Method, In Silico and LC–ESI-MS Analysis of Major Degradation Product, and an In Vitro Biological Safety Study
Finasteride's stability and safety confirmed through precise analytical methods.
research LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery
A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
research LC-APCI+-MS/MS method for the analysis of ten hormones and two endocannabinoids in plasma and hair from the mice with different gut microbiota
The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.
research A new label-free screen for steroid 5α-reductase inhibitors using LC-MS
Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
research LC–MS bioanalytical method for simultaneous determination of latanoprost and minoxidil in the skin
Method measures latanoprost and minoxidil in skin accurately and precisely.
research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS
Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
research Determination of finasteride in human serum by LC-MS/MS
A reliable method was developed to measure finasteride levels in human serum.
research STABILITY INDICATING AN LC-ESI-MS/MS METHOD FOR THE QUANTIFICATION OF MINOXIDIL IN PHARMACEUTICAL DOSAGE FORMS
The method accurately measures Minoxidil in drugs and is reliable for routine use.
research Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Flutamide using LC-MS and GC-MS Spectrometry
Energy healing treatment improved flutamide's solubility and stability, potentially enhancing its effectiveness for prostate cancer.
research Determination of Finasteride in Human Plasma by LC-MS and Study on its Bioequivalent
The two finasteride tablets are bioequivalent.
research Determination of vinflunine in Beagle dog′s plasma by LC-MS and study of its pharmacokinetics
The method accurately measures vinflunine in dog plasma.
research Determination of finasteride in human plasma by LC-MS and its pharmacokinetics
The method accurately measures finasteride in plasma, and the test tablets are as effective as the reference ones.