research A systematic review of antiandrogens and feminization in transgender women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
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750-780 / 1000+ resultsresearch Consequences of Anabolic-Androgenic Steroid Abuse in Males; Sexual and Reproductive Perspective
Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
research Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus
GTx-024 and Danazol affect the uterus like DHT, while GTx-007 has little impact.
research Metabolic, Behavioral, and Reproductive Effects of Vertical Sleeve Gastrectomy in an Obese Rat Model of Polycystic Ovary Syndrome
Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
research Cardiovascular Risk Associated With Gender Affirming Hormone Therapy in Transgender Population
Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.
research Cell-Free Therapies: The Use of Cell Extracts to Mitigate Irradiation-Injured Salivary Glands
Cell extracts may effectively and safely repair radiation-damaged salivary glands.
research Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice
Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.
research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Omega-6 fats in certain cells boost male hormone production.
research Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia
Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research GLP-1 Receptor Analogs: Evidence Linking to Effect on Metabolic and Reproductive Functions in Patients with PCOS and Obesity
GLP-1 receptor analogs may help improve metabolism and reproductive health in people with PCOS and obesity.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Harnessing Microbiome, Bacterial Extracellular Vesicle, and Artificial Intelligence for Polycystic Ovary Syndrome Diagnosis and Management
Microbiome analysis, BEVs, and AI can improve PCOS diagnosis and treatment.
research Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome (PCOS): A Comprehensive Review
Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.
research Impact of Reducing Obesity in PCOS: Methods and Treatment Outcomes
Weight loss improves PCOS symptoms and overall health.
research Obesity in Adults: Position Statement of Polish Association for the Study on Obesity, Polish Association of Endocrinology, Polish Association of Cardiodiabetology, Polish Psychiatric Association, Section of Metabolic and Bariatric Surgery of the Association of Polish Surgeons, and the College of Family Physicians in Poland
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research Serum and hair steroid profiles and their associations with body composition in adolescence
Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.
research GLP-1 RAs and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions
GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.
research Part II. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
Creatine monohydrate is safe and effective for muscle recovery and performance, especially for those with low creatine levels.
research Optimizing Nutrition for PCOS Management: A Comprehensive Guide
Proper nutrition can help manage PCOS symptoms and improve overall health.
research Determining Extracellular Water Effects in Mild and Severe COVID-19 Pneumonia Clinical Course by using the Bioimpedance Method
Extracellular water levels don't indicate COVID-19 pneumonia severity.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Mineral Malnutrition Following Bariatric Surgery
Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
research A Systematic Review of the Effects of Exercise on Hormones in Women with Polycystic Ovary Syndrome
Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
research Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone
Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.