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The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Cathepsin E is crucial for normal skin cell differentiation and development.

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

A new method accurately measures hair lipids, revealing individual differences.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Cathepsin L is essential for normal hair growth and development.

Clascoterone cream could be used for other skin conditions affected by hormones.

848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.

The method accurately measures vitamin E compounds in capsules.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Scientists made two new chemicals that might help treat diseases caused by male hormones.

ILC1-like cells can cause alopecia areata by themselves.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

A man with a rare skin condition and a new gene mutation developed high calcium levels due to his treatment.

α-Tocopheryl acetate is well absorbed through healthy skin.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

Chronic cutaneous lupus erythematosus should be considered when acne treatments don't work.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

A novel CLDN1 mutation in a 2-month-old with NISCH showed improvement with symptom management.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

Targeting LPA could help treat skin disorders.