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Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Menopause can cause skin issues, and seeing a dermatologist helps.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.

Hormonal treatments can effectively improve hidradenitis suppurativa symptoms.

Australia needs better dermatological guidelines for gender-diverse patients.

Hair regrowth treatments had modest benefits for patients with long-term hair loss after chemotherapy.

Both finasteride and GnRH agonist treatments reduced hair growth in women with idiopathic hirsutism, but GnRH agonist was more effective.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

CT scans can find serious prostate cancer even when PSA levels are low.

The document concludes that hair loss in women can be treated with topical treatments or hormone therapy depending on the cause.

Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

Endocrine therapies for cancer significantly increase the risk of hair loss.