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Thorough evaluations and conservative management can lead to positive outcomes in pediatric adrenocortical carcinoma.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

The treatment successfully lowered testosterone levels and reduced symptoms.

A rare ovarian tumor caused a postmenopausal woman to develop male-like features, which improved after surgery.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.

A rare adrenal tumor in a woman only made DHEA-S, causing hair thinning, and was removed, fixing the hormone level.

Enzyme replacement therapy may help alleviate symptoms in complex cases like this.

Mesothelioma of the tunica vaginalis testis is rare, often high-grade, and has a median survival of about 24 months.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

An 86-year-old man with prostate cancer was diagnosed with a rare, low-grade breast cancer and underwent surgery but declined additional hormone therapy.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Trichoblastic carcinoma may be a distinct type of skin cancer different from basal cell carcinoma.

The muscle damage was caused by T-cell large granular lymphocytic leukemia, not dermatomyositis.

Pre-surgical embolization and a two-stage resection improve outcomes for rare sacral tumors.

A woman's pelvic pain and bleeding led to finding and successfully treating a rare benign tumor in her reproductive system.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

A 10-year-old girl's symptoms improved after surgery to remove a benign adrenal tumor.

A painless cheek lump was misdiagnosed but found to be a rare, benign skin lesion called pilomatrixoma, treatable by surgery.

Glibenclamide slows breast cancer cell growth by stopping cell division.

A woman with hair loss had a benign sweat duct tumor found during a scalp biopsy.

A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.

Benign tumors from hair follicles can look like other skin cancers but have distinct features under dermoscopy.

Different growth patterns in thyroid tumors are influenced by where cell growth and death occur.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Removing both ovaries treated the woman's excess male hormone symptoms.

Older patients with new retinal lesions may have cancer, and local radiation might not stop it from spreading.

The man's symptoms improved and the tumor shrank after treatment with cabergoline.

Sonidegib is effective and safe for treating advanced basal cell carcinoma, but biopsies are needed to confirm tumor clearance.