research An Occult Leydig Cell Tumour in a Postmenopausal Woman Presenting with Alopecia and Hirsutism: A Case Report
Surgery removed an ovarian tumor, improving her symptoms and normalizing testosterone levels.
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research Fractional CO2 laser, platelet rich plasma and combination of both in treatment of female pattern hair loss
Combining fractional CO2 laser and PRP is very effective for treating female hair loss.
research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle
Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
research Dose‐response of human follicles during laser‐based hair removal: Ex vivo photoepilation model with classification system embracing morphological and histological features
Higher light doses cause more damage to hair follicles, predicting better hair removal results.
research Low-dose spironolactone in the treatment of female hirsutism.
Low-dose spironolactone is safe and effective for treating hirsutism.
research Laser hair removal
Laser hair removal is now more effective, but the best treatment schedule is still uncertain.
research Hypotrichosis 14: novel variants of the LSS gene in five Chinese families and insights from literature review
New LSS gene variants help understand congenital hypotrichosis 14 better.
research MLL histone methylases in estrogen‐mediated regulation of HOX genes involved in hair follicle development and leukemia
Estrogen and MLL enzymes work together to regulate genes important for hair growth and leukemia.
research Evaluation of Topical Capislow Extract and Long Pulsed Nd-YAG Laser in the Treatment of Idiopathic Hirsutism
Combining capislow with laser is more effective for reducing unwanted hair, but the effect is temporary.
research Compound Heterozygous Mutations in the Hairless Gene in Atrichia with Papular Lesions
Genetic testing for hairless gene mutations is crucial to correctly diagnose and treat atrichia with papular lesions.
research A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family
A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.
research Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline
Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications
Nanocarriers can improve drug delivery through the skin by overcoming barriers.
research Androgen biosynthetic pathways in the human prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research Liarozole—a novel treatment approach for advanced prostate cancer: results of a large randomized trial versus cyproterone acetate
Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.
research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
research The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth?
Understanding EGFR roles could lead to new hair loss treatments.
research The Mechanism of Androgen Actions in PCOS Etiology
Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).
research Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling
Progesterone can reduce seizures without relying on the GABAA receptor pathway.
research The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase?
Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.
research Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRH
GnRH treatment can reduce breast cancer cell invasion.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research Laser-Induced Koebner-Related Skin Reactions: A Clinical Overview
Lasers can trigger skin reactions, especially in darker skin, and more research is needed to improve treatments.
research The Search for the Causes of Common Hyperandrogenism, 1965 to Circa 2015
Significant progress was made in understanding androgen excess disorders, but much is still unknown.
research Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research Impact of androgen deprivation therapy on mortality of prostate cancer patients with COVID-19: a propensity score-based analysis
Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.
research Antiandrogens as Therapies for COVID-19: A Systematic Review
Antiandrogens don't help with COVID-19 and aren't recommended.
research Menopausal Androgen Excess - Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumour (Case Report and Mini-Review of Literature)
High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
research Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients
Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.