research Smoothened antagonists for hair inhibition
Two new compounds were found to effectively reduce hair growth in mice.
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research Characterization of response of murine hair follicle-derived keratinocyte against androgen and testosterone 5α-redactase activity
Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research Cortexolone 17a-propionate: A new antiandrogen acting on hair dermal papilla cells for the treatment of androgenic alopecia
Cortexolone 17a-propionate may be an effective new treatment for hair loss.
research 5 Alpha-Reductase Inhibitor
5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.
research Recent approaches of antibody therapeutics in androgenetic alopecia
Antibody treatments show promise for hair loss but need more research.
research Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells
Diphlorethohydroxycarmalol may help treat hair loss better than current medications.
research Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice
TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
research Central Opioid Inhibition of Neuroendocrine Stress Responses in Pregnancy in the Rat Is Induced by the Neurosteroid Allopregnanolone
In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
research Hirsutism causes and treatments.
Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.
research Myocyte Androgen Receptor Modulates Body Composition and Metabolic Parameters
Activating androgen receptors in muscle can increase muscle mass and reduce fat.
research A homozygous single T deletion found in the GGCX gene with PXE-like phenotypes
A gene mutation worsens skin irritation in mice due to a lack of certain fats.
research Hormone-related hair disorders - from clinical needs to new therapeutic perspectives
New treatments targeting insulin, blood flow, and inflammation could improve hormone-related hair conditions with fewer side effects.
research The serum evaluation of sex hormones including DHEAs, DHT, testosterone in oral lichen planus patients
Sex hormones do not cause oral lichen planus.
research The Antiandrogenic Action of 4–Androsten–3–one–17β– Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ1
The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
research Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Efficacy and tolerability of HDMHG0401-10 in Patients with Androgenetic Alopecia-A Randomized Double-blind Placebo-controlled Trial
HDMHG0401-10 improves hair loss in men with androgenetic alopecia and has no major side effects.
research The Evaluation and Treatment of Hirsute Women
Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
research Percutaneous absorption of a new antiandrogen included in liposomes or in solution
Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
research Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth
MR antagonists may improve skin health and wound healing, especially in aging.
research Hair Growth Promotion by δ-Opioid Receptor Activation
Activating δ-opioid receptors can help hair grow.
research Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase
Some dibenzo compounds might help treat cancer with fewer side effects.
research Canine Alopecia Secondary to Human Topical Hormone Replacement Therapy in Six Dogs
Dogs exposed to their owners' hormone therapy developed hair loss, but symptoms resolved after stopping the therapy.
research Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling
Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants
Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.
research Low-Dose Flutamide (125 mg/Day) as Maintenance Therapy in the Treatment of Hirsutism
Low-dose flutamide effectively maintains reduced hirsutism with no side effects.
research Safety and Effectiveness of a Novel Hyaluronic Acid Gel for Lip Augmentation
The new hyaluronic acid gel is as safe and effective for lip enhancement as the existing product.
research Targeting hirsutism: a new approach*1
Eflornithine cream effectively reduces facial hair in women with hirsutism.
research Finasteride/testosterone undecanoate
Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.