Search

everythinglearnresearchcommunity

for

Search:↓

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Specific mutations in a receptor cause facial abnormalities and hair loss.

Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.

Caribine from traditional Chinese medicine may help treat hair loss.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Procyanidin B2 and leucopelargonidin from Saraca asoca may help treat PCOS by balancing hormones.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

The vitamin D receptor can affect gene activity even without its usual hormone in hair and skin.

Parsley contains compounds that might be good for treating hair loss.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Teicoplanin may help treat hair loss by reducing androgen receptors and boosting hair cell growth.

Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.