41 citations
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September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
40 citations
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June 2013 in “Scientific Reports” A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
39 citations
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October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
37 citations
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April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
37 citations
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January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
31 citations
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April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
29 citations
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May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
28 citations
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October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
28 citations
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December 2012 in “The American Journal of Cosmetic Surgery” Proteins from stem cells improved hair growth in patients with hair loss.
28 citations
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March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
26 citations
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April 2011 in “Skin Research and Technology” In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
25 citations
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September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
25 citations
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April 2012 in “Acta Biomaterialia” Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
24 citations
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May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
24 citations
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March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
23 citations
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January 2024 in “Nature Immunology” γδ T cells adapt uniquely to different tissues in mice.
23 citations
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January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
23 citations
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June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
22 citations
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November 2017 in “Scientific Reports” The pituitary gland functions normally even after losing most SOX2+ stem cells.
22 citations
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June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
22 citations
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November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
22 citations
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October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
21 citations
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December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
21 citations
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November 2010 in “Journal of molecular medicine” FoxN1 gene is essential for proper thymus structure and preventing hair loss.
20 citations
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November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
19 citations
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April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
17 citations
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December 2013 in “PLoS ONE” The postnatal thymus has cells like mesenchymal stem cells that can become different cell types and help maintain thymus structure.