October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
44 citations
,
February 2012 in “The journal of neuroscience/The Journal of neuroscience” Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.
102 citations
,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
94 citations
,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
33 citations
,
January 2001 in “Critical care clinics” Dietary lipids affect inflammation and are crucial for normal cell function and immune health.
33 citations
,
March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
1 citations
,
October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
92 citations
,
April 2021 in “Pharmaceutics” Characterizing lipid nanoparticles is challenging due to issues with sensitivity, reproducibility, and reliability.
55 citations
,
January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
50 citations
,
December 2000 in “Journal of Pharmaceutical Sciences” Hair follicles significantly enhance electroosmotic transport during iontophoresis.
47 citations
,
November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
41 citations
,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
36 citations
,
September 2019 in “Journal of Herbal Medicine” Herbal nano-formulations show potential for effective skin delivery but need more research.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
6 citations
,
May 2023 in “European journal of pharmaceutical sciences” Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
2 citations
,
April 2021 in “International Journal of Pharmaceutics” Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
1 citations
,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
3 citations
,
January 2017 in “Acta Dermato Venereologica” Lipid-antigen stimulation may play a role in folliculotropic mycosis fungoides.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
5 citations
,
January 2003 in “Oilseeds and fats, crops and lipids/OCL. Oilseeds & fats crops and lipids” Vegetable protein lowers cholesterol and protein deficiency can cause health issues.
4 citations
,
February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
April 2025 in “Journal of Cosmetic Dermatology” Managing lipids may help treat hair loss.
March 2021 in “Research Square (Research Square)” The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
137 citations
,
January 2000 in “Skin Pharmacology and Physiology” The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.
91 citations
,
July 2022 in “Frontiers in Endocrinology” Different PCOS characteristics affect lipid profiles, increasing cardiovascular disease risk, so regular lipid screening is advised.