December 2025 in “MEDFARM Jurnal Farmasi dan Kesehatan” Topical metformin shows promise for treating skin conditions like acne and psoriasis.
July 2024 in “International Journal of Chemical and Biological Sciences” Glypican-4 may help indicate insulin sensitivity and lipid issues in women with PCOS.
September 2023 in “Research Square (Research Square)” Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.
December 2021 in “Signal transduction and targeted therapy” Increasing sebum production might help reduce fat and improve metabolism.
Guaraná extract effectively reduces oiliness in skin and hair without harming skin health.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” DHT may reduce inflammation caused by certain bacteria in skin cells.
December 2013 in “Biomedical and biopharmaceutical research” Nanotechnology shows promise for better drug delivery and cancer treatment.
13 citations
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October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
86 citations
,
June 2017 in “Anais Brasileiros de Dermatologia” Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
76 citations
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April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
47 citations
,
September 2015 in “Journal of Drug Delivery Science and Technology” Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
36 citations
,
October 2014 in “Langmuir” Bleaching hair removes its protective top layer and exposes more hydrophilic groups, changing its chemical surface and affecting how it interacts with products.
25 citations
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July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
5 citations
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August 2018 Plant extracts can benefit skin but must be safe and high-quality.
4 citations
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February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
September 2025 in “Turkish Journal of Dermatology” Oxidative stress may play a role in alopecia areata, but depression and suicide risk are similar to healthy peers.
January 2016 in “SpringerBriefs in bioengineering” Genetic defects and UV radiation cause skin damage and aging.
19 citations
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December 2018 in “Experimental and Molecular Medicine” Small molecule IM boosts hair growth by changing stem cell metabolism.
6 citations
,
November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
30 citations
,
December 2019 in “PLoS ONE” The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
17 citations
,
May 2021 in “Journal of Applied Pharmaceutical Science” Transferosomes effectively deliver drugs through the skin, improving treatment for skin disorders.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
12 citations
,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
10 citations
,
April 2019 in “Environmental Science and Pollution Research” Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
9 citations
,
October 2008 in “Mutation research” N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
6 citations
,
January 2020 in “International journal of biological sciences” Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
February 2026 in “Journal of Sylva Indonesiana” Avicennia marina heartwood extract shows strong antioxidant potential for health benefits.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” Gray hair requires special coloring techniques and care to maintain quality and strength.
May 2024 in “Journal of drug delivery and therapeutics” Women with PCOS have higher oxidative stress and hormone imbalances, suggesting managing oxidative stress could help.