22 citations
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June 2002 in “Journal of Medicinal Chemistry” Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
54 citations
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June 2020 in “Pharmaceutics” New nanocarriers improve drug delivery for disease treatment.
5 citations
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July 2020 in “JAMA Dermatology” Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.
9 citations
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December 2018 in “JAAD case reports” Lipedematous alopecia involves a thickened scalp and hair loss, with limited effective treatments available.
12 citations
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March 2020 in “Journal of Bioactive and Compatible Polymers” Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
68 citations
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July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
35 citations
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February 2003 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Lead can help reveal and organize lipids in human hair.
3 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” The substances improved hair regrowth and protected hair cells in humans and mice.
6 citations
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August 2013 in “한국응용생명화학회지” Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
September 2002 in “Research Repository (Kingston University London)” Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.
13 citations
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January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
646 citations
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October 2015 in “Plant Cell & Environment” Lipids help plants respond to stress by triggering important signals.
February 2025 in “medRxiv (Cold Spring Harbor Laboratory)” GLP-1 agonists may increase the risk of hair loss.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
3 citations
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February 2016 in “Endocrinology and Metabolism Clinics of North America” Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.
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August 2021 in “Journal of pharmaceutical research international” Fenugreek seed extract in a nanoparticle gel could be a promising new treatment for hair loss.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” The study created a new hair loss treatment paste that regrows hair faster and with fewer side effects than minoxidil alone.
January 2024 in “Circulation” Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
July 2025 in “Scientific Reports” Pioglitazone, Trimipramine, and Dimetindene may be repurposed to treat psoriasis.
39 citations
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November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
2 citations
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September 2025 in “Future Journal of Pharmaceutical Sciences” Lupeol shows promise for hair growth but needs better absorption and safety testing.
105 citations
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December 2009 in “Archives of dermatology” A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.
April 2025 in “European Journal of Pharmaceutics and Biopharmaceutics” The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.
6 citations
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January 2025 in “Journal of Materials Chemistry B” Liposome-composite hydrogel microspheres are promising for safe, controlled drug delivery.
26 citations
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June 2011 in “International Journal of Pharmaceutics” SLN suspensions work as well as commercial solutions for minoxidil delivery, but are non-corrosive, making them a promising alternative.
48 citations
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September 2007 in “European Journal of Neuroscience” Ethanol blocks memory formation in rats by enhancing certain brain chemicals.
Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.