research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
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540-570 / 1000+ resultsresearch Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.
research Penetration Enhancement of Topical Formulations
New methods improve how well skin treatments work by helping drugs get through the skin barrier.
research Liposomes in dermatological diseases
Liposomes are useful for treating skin conditions by effectively delivering drugs.
research Follicles, fungi and scalp conditions
Malassezia yeast plays a key role in dandruff and seborrhoeic dermatitis.
research A review on ethosomes promising as novel drug delivery systems
Ethosomes improve drug delivery through the skin but face stability challenges.
research Development of Artificial Sebum-containing Leeming and Notman Agar Medium to Enhance the Growth of Malassezia
A new growth medium doubles Malassezia restricta yield by using artificial sebum.
research Folate bioavailability in reconstructed skin models and effects of folate in a monolayer wound healing assay. Approaches on topic application
Topical folates can penetrate skin and enhance wound healing.
research Microemulsions as a Surrogate Carrier for Dermal Drug Delivery
Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Keratin film made of human hair as a nail plate model for studying drug permeation
Keratin films from human hair can potentially replace human nail plates for drug testing.
research GABAergic neurosteroids mediate the effects of ethanol on long‐term potentiation in rat hippocampal slices
Ethanol blocks memory formation in rats by enhancing certain brain chemicals.
research Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals
The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
research Liposomes in cancer therapy
Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
research The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model
Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
research Tumescent Local Anesthesia
Tumescent local anesthesia is a safe, cost-effective method for outpatient liposuction.
research Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs
Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
research Synthesis and structure–activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research Niosomes as Efficient Nanocarriers for Targeted Drug Delivery
Niosomes are effective carriers for targeted drug delivery, improving drug stability and efficiency.
research Ethosomes: An Exciting and Promising Alcoholic Carrier System for Treating Androgenic Alopecia
Ethosomes are a promising method for treating hair loss by delivering drugs directly to the scalp.
research Traditional Scraping (Gua Sha) Combined with Copper‐Curcumin Nanoparticle Oleogel for Accurate and Multi‐Effective Therapy of Androgenic Alopecia
Using a special gel with copper and curcumin along with a scraping massage technique improved hair growth better than the common hair loss treatment, minoxidil.
research Preparation of particles for cosmetic applications in human hair
PLA nanoparticles can effectively deliver treatments to hair follicles, showing potential for hair therapy.
research Persistent scurvy after vitamin C supplementation in a high-risk patient: a case report
Vitamin C deficiency can persist in high-risk patients despite supplementation.
research Corkscrew hairs
The woman has scurvy and needs more vitamin C.
research SCURVY PRESENTING WITH CUTANEOUS AND ARTICULAR SIGNS AND DECREASE IN RED AND WHITE BLOOD CELLS
Vitamin C is essential to prevent scurvy and its symptoms.
research Stability Studies on L-Ascorbic Acid dl-α-Tocopherol Phosphoric Acid Diester Potassium Salt (EPC-K)
EPC-K is stable except at very acidic pH or when exposed to sunlight, and it can decompose in low ethanol concentrations.
research P144 Vitamin C deficiency in inflammatory bowel disease: the forgotten micronutrient
Many people with inflammatory bowel disease have a vitamin C deficiency, which can lead to scurvy symptoms.
research The Identity of Flavin with the Cataract-Preventive Factor
Flavin prevents cataracts in young rats.
research Nonalimental Scurvy With Relapse Symptoms After Stopping Oral Vitamin C Supplementation
A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.
research Bleeding tendency with corkscrew hair
Low vitamin C caused bleeding and corkscrew hair, resolved with vitamin C treatment.