February 2018 in “Medical Hypotheses” Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.
411 citations
,
April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
291 citations
,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
204 citations
,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
103 citations
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October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
75 citations
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November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
62 citations
,
December 2015 in “Clinical Medicine” Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).
61 citations
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June 2016 in “Clinical Medicine” PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.
51 citations
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October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
50 citations
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April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
42 citations
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July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
39 citations
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August 2004 in “International journal of gynaecology and obstetrics” Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
36 citations
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September 2018 in “American Journal of Clinical Dermatology” Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.
34 citations
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April 2008 in “Journal of the European Academy of Dermatology and Venereology” Skin problems like itching, dry skin, and hair loss are more common in hepatitis C patients after interferon treatment, but lichen planus is not linked to the infection.
27 citations
,
December 2016 in “Dermatology and Therapy” Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
24 citations
,
September 2020 in “Dermatology and therapy” Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.
23 citations
,
January 2019 in “International Journal of Dermatology” Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
18 citations
,
August 2011 in “Clinical Drug Investigation” Low-dose isotretinoin combined with pulsed azithromycin cleared acne in most patients, with mild side effects.
18 citations
,
January 2003 in “Gynecological Endocrinology” Low-dose finasteride effectively reduces hirsutism without serious side-effects.
17 citations
,
May 2018 in “Journal of Cosmetic Dermatology” Most women in the study lost hair due to chronic shedding, with stress and nutrient deficiencies being common factors.
17 citations
,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
16 citations
,
April 2007 in “Journal of Obstetrics and Gynaecology Research” Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
14 citations
,
March 2014 in “Journal of The American Academy of Dermatology” Symmetrical Acrokeratoderma (SAK) may be a unique skin condition in China, lacking specific treatment and needing long-term monitoring.
11 citations
,
May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
10 citations
,
February 2016 in “The Journal for Nurse Practitioners” Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.
10 citations
,
June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
8 citations
,
April 2020 in “European Journal of Nutrition” Newborns' hair shows how much caffeine their mothers drank during pregnancy.
8 citations
,
October 2019 in “Dermatologic Therapy” Bicalutamide improves hair density in women safely.
7 citations
,
September 2018 in “Aesthetic surgery journal” Deoxycholic acid effectively reduces double chin fat with temporary side effects and high patient satisfaction.
6 citations
,
April 2019 in “Journal of Pediatric Endocrinology and Metabolism” Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.