research Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
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research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
research Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor
Curcumin, EGCG, barringtozenol, and finasteride are effective VEGFR inhibitors.
research Case Report: Diffuse Hypertrichosis in the Course of Hepatitis C Treatment by IFN-α and Ribavirin
A man developed excessive hair growth after treatment with interferon-alpha and ribavirin for hepatitis C.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1
MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements
Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
research Risk of valproic acid-related alopecia: A systematic review and meta-analysis
Valproic acid increases the risk of hair loss more than other drugs, especially in migraine patients, and lamotrigine may be a safer alternative.
research Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors
Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
research High Cadmium Levels in Cured Meat Products Marketed in Nigeria - Implications for Public Health
Cured meats in Nigeria have high cadmium levels, posing health risks.
research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Androgenetic alopecia: the role of inflammation and Demodex
Inflammation and Demodex mites might contribute to hair loss, and targeting them could help treat it.
research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration
Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
research Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices
Future work on macrolide antibiotic analysis will aim to enhance selectivity, sensitivity, and efficiency using advanced chromatographic methods.
research Changes in European Legislation Make it Timely to Introduce a Transparent Market Surveillance System for Cosmetics
Europe needs a clear system to watch over cosmetics for safety and to make sure product claims are true.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
Solanum nigrum shows promise for treating COVID-19 and its complications, but more research is needed.
research A comprehensive review of biochemical factors in herbs and their constituent compounds in experimental studies on alopecia
Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
research Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician, and the pharmaceutical companies
The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
research Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome
A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.
research The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Anti-inflammatory and anti-hyperplastic effect of Bazhengsan in a male rat model of chronic nonbacterial prostatitis
Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
research Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
research Drug-induced skin reactions: a pathologist viewpoint
Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Refractory shock following ingestion of topical minoxidil solution
A man experienced life-threatening shock after swallowing hair growth solution.
research Immunosuppressive therapy in autoimmune disease — A review
Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
research Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches
Using existing drugs for new treatments is cost-effective and safer.
research Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm
CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.