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K15 Promoter-Driven Enforced Expression of NKIRAS Exhibits Tumor Suppressive Activity Against the Development of DMBA/TPA-Induced Skin Tumors

research K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

4 citations , October 2021 in “Scientific Reports”

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

research LB1056 Phase 1b: Translational evaluation of VYN201, a pan-BD BET inhibitor, for the treatment of non-segmental vitiligo

1 citations , July 2024 in “Journal of Investigative Dermatology”

VYN201 shows promise as a safe and effective treatment for non-segmental vitiligo.

research Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling

40 citations , May 2005 in “Journal of Cell Science”

Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.

research Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

19 citations , May 2016 in “Matrix Biology”

Deleting a specific protein in skin cells disrupts normal hair growth and development.

research A machine learning and network framework to discover new indications for small molecules

8 citations , August 2020 in “PLOS Computational Biology”

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

research NAC transcription factor RD26 is a regulator of root hair morphogenic plasticity

1 citations , April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

RD26 controls root hair growth during drought by repressing key genes, helping plants save energy.

research Hemidesmosomes and Notch signaling regulate epidermal differentiation via delamination

April 2026 in “Development”

Hemidesmosomes and Notch signaling help skin cells mature by moving them to the outer layer.

research The Use of a Light-Emitting Diode Device for Neck Rejuvenation and Its Safety on Thyroid Glands

11 citations , April 2021 in “Journal of Clinical Medicine”

The LED device safely improves neck skin appearance without affecting thyroid function.

research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome

3 citations , May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

Cthrc1 Deficiency Aggravates Wound Healing and Promotes Cardiac Rupture After Myocardial Infarction via Non-Canonical WNT5A Signaling Pathway

research Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway

9 citations , January 2023 in “International Journal of Biological Sciences”

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

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