Search

for
Search:

Sort by

Research

390-420 / 1000+ results

Comparative Investigation of Immune-Related Biomarkers in Alopecia Areata Subtypes

research Comparative investigation of immune-related biomarkers related to alopecia areata subtypes

September 2024 in “Archives of Medical Science”

Alopecia areata is linked to immune system differences, with specific biomarkers like CXCL9 and CXCL10 being key for diagnosis and potential treatment targets.

research A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

103 citations , March 2015 in “Nature Communications”

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

KRTAP 2-3 as a Novel Potential Biomarker of Cells in the Polyaneuploid Cancer Cell State to Predict Cancer Recurrence

research Abstract 2205: KRTAP 2-3 is a novel potential biomarker of cells in the polyaneuploid cancer cell (PACC) state to predict cancer recurrence

April 2023 in “Cancer research”

KRTAP2-3 could help predict cancer recurrence by identifying specific cancer cells.

The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

research The E211 G>A Androgen Receptor Polymorphism Is Associated with a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

76 citations , April 2005 in “Cancer Epidemiology, Biomarkers & Prevention”

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

The Evaluation of IL-4 VNTR Intron 3 and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case–Control Study

research The evaluation of IL-4 VNTR intron 3 and TNF-α (rs1799964) gene polymorphisms in Egyptian patients with alopecia areata: a case–control study

July 2024 in “Egyptian Journal of Medical Human Genetics”

These gene variations are not linked to alopecia areata in Egyptians.

research 479 Transcriptomics identifies potential novel therapeutic targets in androgenetic alopecia

April 2017 in “Journal of Investigative Dermatology”

Found new possible treatments for hair loss.

research The Study on Biological Function of Keratin 26, a Novel Member of Liaoning Cashmere Goat Keratin Gene Family

14 citations , December 2016 in “PloS one”

Keratin 26 affects cashmere goat hair growth and is influenced by various treatments.

research The genetic evolution of skin squamous cell carcinoma: tumor suppressor identity matters

6 citations , May 2016 in “Experimental Dermatology”

The type of tumor suppressor gene lost affects the behavior of skin cancer.

research Identification and characterization of genes for skin and hair disorders

February 2026 in “bonndoc (University of Bonn)”

New gene variants were found for rare skin and hair disorders, improving understanding and treatment.

research The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis

10 citations , December 2008 in “Molecular Carcinogenesis”

The PML protein helps prevent skin cancer in mice.

research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model

8 citations , March 2023 in “International Wound Journal”

IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.

research Identification of Hypoxia and Mitochondrial-related Gene Signature and Prediction of Prognostic Model in Lung Adenocarcinoma

6 citations , January 2024 in “Journal of Cancer”

A gene-based model predicts lung adenocarcinoma outcomes and helps guide treatment decisions.

Case of Autosomal Recessive Woolly Hair/Hypotrichosis with Compound Heterozygous Mutations in the LIPH Gene at c.742C > A and c.614A > G: The First Japanese Case

research Case of autosomal recessive woolly hair/hypotrichosis with compound heterozygous mutations in the LIPH gene at c.742C > A and c.614A > G: The first Japanese case

February 2023 in “Journal of dermatology”

The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.

Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

research Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

32 citations , May 2012 in “PloS one”

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

research Identification and characterization of four immune-related signatures in keloid

11 citations , July 2022 in “Frontiers in Immunology”

Four specific genes are linked to keloid formation and could be potential treatment targets.

research Frequent downregulation of DMBT1 and galectin‐3 in epithelial skin cancer

48 citations , March 2003 in “International Journal of Cancer”

DMBT1 and galectin-3 may help suppress epithelial skin cancer.

research Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia

13 citations , April 2010 in “Journal of dermatological science”

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

Integrating Single-Cell and Spatial Transcriptomics of Human Hair Follicles to Define Transcriptional Signature of Follicular Dermal Papilla

research 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

The research identified specific genes that are active in the cells crucial for hair growth.

research CCN2 modulates hair follicle cycling in mice

21 citations , October 2013 in “Molecular Biology of the Cell”

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

research Atrichia with Papular Lesions in a Chinese Family Caused by Novel Compound Heterozygous Mutations and Literature Review

3 citations , January 2013 in “Dermatology”

New genetic mutations causing hair loss were found in a Chinese family.

research Identification of the Rat Rex Mutation as a 7-bp Deletion at Splicing Acceptor Site of the Krt71 Gene

45 citations , January 2010 in “Journal of Veterinary Medical Science”

A gene mutation causes curly hair and hair loss in rats.

research CD271 orchestrates skin structure, differentiation, and inflammation via PI3K/Akt and PKCα/ERK pathways

October 2025 in “Cell Death and Disease”

CD271 is crucial for maintaining healthy skin and preventing inflammation.

Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

2 citations , July 2019 in “PLOS ONE”

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

research Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

19 citations , July 2020 in “EBioMedicine”

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

research 131 Mutational landscape of extramammary Paget disease

April 2018 in “Journal of Investigative Dermatology”

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.