January 2009 in “Egyptian Journal of Medical Human Genetics” The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
Off-label drug use can be risky but sometimes beneficial when standard treatments fail.
July 2018 in “British Journal of Dermatology” Mindfulness reduces anxiety and depression in skin disease patients; dermatologists and psychiatrists often lack confidence in treating psychodermatological conditions.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
271 citations
,
June 2013 in “Human Reproduction” PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.
150 citations
,
October 2012 in “Clinical Endocrinology” Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.
120 citations
,
October 2004 in “International journal of radiation oncology, biology, physics” Higher doses of cranial irradiation are linked to permanent hair loss.
109 citations
,
November 2004 in “Lupus” The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.
96 citations
,
September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
88 citations
,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
84 citations
,
February 2013 in “Clinica chimica acta” Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
81 citations
,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
76 citations
,
April 2005 in “Cancer Epidemiology, Biomarkers & Prevention” E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.
74 citations
,
January 2013 in “Journal of Investigative Dermatology” Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
71 citations
,
July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
63 citations
,
January 2017 in “Annals of Dermatology” More research is needed to understand alopecia areata severity.
62 citations
,
January 2013 in “Skin Pharmacology and Physiology” Low iron and vitamin D levels are linked to hair loss in women.
59 citations
,
August 2018 in “The oncologist” Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.
59 citations
,
February 2021 in “BMJ” High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
53 citations
,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.
52 citations
,
November 2009 in “International journal of gynaecology and obstetrics” High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
49 citations
,
March 2018 in “Toxicological sciences” Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
49 citations
,
March 2009 in “Archives of Gynecology and Obstetrics” Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.
48 citations
,
January 2018 in “Scientific Reports” Hair analysis can reveal metabolic changes and potential pregnancy complications.
48 citations
,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
46 citations
,
August 2016 in “Journal of The American Academy of Dermatology” The study found that family history, personal history of adolescent acne, no pregnancies, hirsutism, office work, stress, and low intake of fruits/vegetables and fish are risk factors for adult female acne.
41 citations
,
June 2018 in “Journal of The American Academy of Dermatology” Some treatments for folliculitis decalvans work well, with tetracyclines and a mix of rifampicin and clindamycin being most effective.
39 citations
,
February 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
37 citations
,
January 2016 in “Australasian Journal of Dermatology” Scalp melanomas are more dangerous and often missed, needing earlier detection.
35 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.