508 citations
,
June 2009 in “Current drug metabolism” Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.
February 2012 in “Australasian Journal of Dermatology” Some moles can disappear naturally, maintenance therapy for Stage 1 mycosis fungoides may not be necessary, allergic skin reactions in children are rising, weekly methotrexate for psoriasis is more effective than daily, long-term finasteride use improves hair growth with few side effects, and petrolatum improves UV therapy for psoriasis.
November 2024 in “Journal of the European Academy of Dermatology and Venereology” Long-term baricitinib treatment can lead to significant scalp hair regrowth in patients initially showing only eyebrow or eyelash regrowth.
Long-term finasteride use may affect sperm structure and chromosomes.
2 citations
,
December 2021 in “BMC veterinary research” Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
December 2004 in “Neuropsychopharmacology” Long-term alcohol exposure alters brain receptor function differently in various brain regions.
35 citations
,
May 2023 in “International Journal of Preventive Medicine” Long COVID causes lasting symptoms and needs vaccines for prevention and a team approach for treatment.
68 citations
,
April 2002 in “Journal of Human Nutrition and Dietetics” The intensive conventional diet with exercise led to better long-term weight loss and health improvements than the very low calorie diet in obese type 2 diabetics.
15 citations
,
November 2007 in “Journal of Neurochemistry” Stopping alcohol after long-term use causes anxiety and changes brain chemicals.
6 citations
,
January 2019 in “Dermatology Research and Practice” Many survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo suffer long-term eye and skin problems.
August 2004 in “Medisch-Farmaceutische Mededelingen” Long-term use of finasteride may cause breast cancer in men.
January 2002 in “Actas Dermo-Sifiliográficas” Long-term use of hormonal supplements can cause hair loss in women.
2 citations
,
January 2021 in “Cureus” Long-term anabolic steroid use can lead to heart and metabolic health issues.
17 citations
,
December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
6 citations
,
March 2015 in “European Journal of Public Health” Long-term hair dye use may increase testosterone levels in women.
1 citations
,
January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
March 2023 in “Journal of Pakistan Association of Dermatologists” Long-term use of topical steroids can cause rosacea, but switching treatments can improve symptoms.
June 2006 in “American Journal of Epidemiology” Long-term diabetes is linked to lower prostate cancer risk.
Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.
94 citations
,
January 2007 in “Cutaneous and Ocular Toxicology” Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.
3 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” PRP improves short-term pain and function in shoulder injuries, but long-term benefits are unclear.
October 2020 in “Journal of Pakistan Association of Dermatology” Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
Finasteride is a safe and effective long-term treatment for male hair loss, especially when started early.
101 citations
,
January 2014 in “Journal of Visualized Experiments” The method effectively measures long-term stress levels using hair samples.
June 2017 in “Journal of Clinical and Health Sciences” A woman developed folliculitis after long-term acitretin treatment for pustular psoriasis.
19 citations
,
July 2009 in “Clinical and Experimental Dermatology” The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
737 citations
,
August 2020 in “Journal of Infection” Many COVID-19 survivors experience long-term symptoms but still report satisfactory quality of life and return to work.
1 citations
,
August 2023 in “Frontiers in immunology” Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
1 citations
,
October 2010 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” The skin fully recovered after using the optical clearing agent, showing no long-term harm.