research Potential mechanisms of exercise in maintaining skin homeostasis disrupted by protein deficiency (Review)
Exercise helps maintain healthy skin by promoting regeneration and reducing inflammation.
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research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Editor’s picks January 2021
PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.
research Can Pension Funds Partially Manage Longevity Risk by Investing in a Longevity Megafund?
Investing in a longevity megafund can help pension funds reduce longevity risk.
research Advances in Longevity: The Intersection of Regenerative Medicine and Cosmetic Dermatology
Cosmetic dermatology is improving with new technologies but faces ethical and regulatory challenges.
research Evaluation of Derma Genie™-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects
Derma Genie™-H001 can help prevent hair loss and promote hair growth.
research Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells
Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice
Low selenium levels can extend lifespan but worsen health issues.
research Protective Effects of Schinus terebinthifolius Leaf Supercritical Fluid Extract Against UVC-Induced Oxidative Stress: A Com-Prehensive Gene Expression Study
Brazilian pepper tree leaf extract effectively protects skin cells from UVC damage and is a strong natural skincare option.
research Do Changes in Chromosomes Cause Aging?
Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
research Hair-specific expression of chloramphenicol acetyltransferase in transgenic mice under the control of an ultra-high-sulfur keratin promoter.
The study showed that a specific DNA sequence can control gene expression in hair growth areas of mice.
research Genetic Basis of Male Pattern Baldness
Male pattern baldness is largely genetic, linked to the androgen receptor gene, and may relate to certain health issues.
research Superior Root Hair Formation Confers Root Efficiency in Some, But Not All, Rice Genotypes upon P Deficiency
Some rice types grow better roots for phosphorus uptake, but not all do.
research Removing all obstacles: A critical role for p53 in promoting tissue renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
research Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Whole transcriptome sequencing of different hair types in inner Mongolian cashmere goats
Hair type differences in cashmere goats are linked to keratin and cytoskeletal organization.
research The Effects of Spermidine on Functional and Transcriptomic Markers in Human Primary Keratinocytes
Spermidine may improve skin health and hair growth by enhancing cell function.
research Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26
Hair loss gene found on chromosome 3q26.
research Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter
Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Molecular Genetics of Keratinization Disorders – What’s New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
research Role of regeneration in tissue repairing and therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita
Loss of Ten1 in mice causes telomere shortening and symptoms similar to human dyskeratosis congenita.
research Premature Graying of Hair: A Comprehensive Review and Recent Insights
Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
research Gray Hair: From Preventive to Treatment
Gray hair can potentially be managed or reversed with treatments that boost melanin production and address nutritional deficiencies.
research Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research The Chicken Frizzle Feather Is Due to an α-Keratin (KRT75) Mutation That Causes a Defective Rachis
A mutation in the KRT75 gene causes frizzle feathers in chickens.
research ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.