18 citations
,
May 2006 in “Journal of Cutaneous Medicine and Surgery” Linear lichen planopilaris can affect the trunk, not just the face.
10 citations
,
June 2019 in “Case reports in dermatology” LALPS causes non-scarring hair loss along the Blaschko line, with unique trichoscopic findings.
16 citations
,
December 2017 in “Journal of The American Academy of Dermatology” Low-level laser therapy may reduce symptoms and increase hair thickness in lichen planopilaris patients.
September 2021 in “CRC Press eBooks” Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
1 citations
,
May 2022 in “Journal of Drugs in Dermatology” Low-dose naltrexone and platelet-rich plasma can regrow hair in lichen planopilaris.
1 citations
,
September 2020 in “Journal of Dermatological Science” The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
1 citations
,
July 2022 in “PLOS ONE” The study concluded that people with Lichen Planopilaris have a more diverse scalp bacteria and different metabolic pathways compared to healthy individuals.
January 2026 in “JPRAS Open” PDLLA scalp injections improved hair regrowth in most patients with non-scarring alopecia.
January 2017 in “Postepy Dermatologii I Alergologii” The CRH/CRH-R1 system might be involved in causing lichen planus.
17 citations
,
October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
12 citations
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June 2020 in “Journal of The American Academy of Dermatology” Platelet-rich plasma is tolerable for lichen planopilaris and doesn't worsen the condition, but its effectiveness is unclear.
Patients with lichen planopilaris have a higher risk of heart disease.
April 2019 in “Journal of Investigative Dermatology” Blocking LFA-1 prevents hair loss in mice.
September 2022 in “The American Journal of Dermatopathology” Blocking IL-17 might help treat the hair loss condition Lichen planopilaris.
76 citations
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June 2008 in “Journal of the American Academy of Dermatology” The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
1 citations
,
March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
April 2026 in “American Journal of Dermatopathology” Increased blood vessel growth in lichen planopilaris may signal active disease needing aggressive treatment.
January 2025 in “Medical Research Archives” Low-level laser therapy can help with inflammation but isn't widely accepted yet.
December 2024 in “Biochemical and Biophysical Research Communications” LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.
2 citations
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December 2011 in “[Thesis]. Manchester, UK: The University of Manchester; 2011.” Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
29 citations
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March 2016 in “Dermatologic therapy” Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
12 citations
,
March 2019 in “Lasers in Surgery and Medicine” Low-level laser therapy improves hair growth and dermal papilla cell function.
29 citations
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September 2018 in “Journal of the American Heart Association” EP 2 receptor is essential for heart repair by helping macrophages work properly.
1 citations
,
November 2025 in “Clinical and Experimental Medicine” lncRNAs are important for understanding and treating skin diseases.
1 citations
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March 2013 in “Journal of Dermatological Case Reports” A rare skin condition affected only the facial hair of a 46-year-old man.
38 citations
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January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.