8 citations
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June 2024 in “Pharmaceutics” PEA-ENL improves skin delivery and reduces inflammation without side effects.
8 citations
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September 2021 in “Facial plastic surgery & aesthetic medicine” Low-level light/laser therapy is effective in treating male and female pattern hair loss without side effects.
14 citations
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October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
September 2016 in “Journal of Dermatological Science” Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.
20 citations
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September 2003 in “Journal of Investigative Dermatology” Targeting MIG and MCP-1 may help treat inflammation in alopecia areata.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Two sisters with lipoedematous scalp suggest a genetic influence in the condition.
1 citations
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July 2025 in “Journal of Investigative Dermatology” IL-27 may help prevent hair loss by creating immune-suppressing cells.
40 citations
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December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
ILC1-like cells may contribute to hair loss in alopecia areata.
8 citations
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June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
36 citations
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April 2016 in “British journal of dermatology/British journal of dermatology, Supplement” A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
91 citations
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December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
165 citations
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September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Some people with the skin color loss condition, vitiligo, also develop the skin inflammation condition, lichen planus, possibly due to local trauma, sun damage, or genetic factors.
5 citations
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January 2021 in “Veterinary dermatology” Low-level laser therapy did not reduce licking or improve lesions in dogs with ALD but did increase hair growth.
July 2024 in “Journal of Investigative Dermatology” CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.
1 citations
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August 2016 in “Journal of Investigative Dermatology” Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
5 citations
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February 2025 in “Frontiers in Immunology” Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
7 citations
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March 2011 in “Hormone and Metabolic Research” Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
1 citations
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January 2020 in “Skin Appendage Disorders” Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Periplaneta americana extract helps hair regrowth in alopecia areata by reducing inflammation and balancing skin bacteria.
October 2025 in “Cell Death and Disease” CD271 is crucial for maintaining healthy skin and preventing inflammation.
82 citations
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July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
April 2025 in “Journal of Investigative Dermatology” Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.
3 citations
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October 2021 in “Journal of Cosmetic Dermatology” Trichoscopy helps tell apart Frontal Fibrosing Alopecia and Lichen planopilaris by showing different hair and scalp features.
14 citations
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June 2022 in “Neuroscience” 9 citations
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July 2022 in “Journal of Biological Chemistry” WWP2 is crucial for tooth development in mice.