479 citations
,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
181 citations
,
January 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
169 citations
,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
38 citations
,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
7 citations
,
July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
July 2025 in “Journal of Investigative Dermatology” Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.
415 citations
,
January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
39 citations
,
September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
33 citations
,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
16 citations
,
July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
67 citations
,
December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
44 citations
,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
27 citations
,
February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
20 citations
,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
13 citations
,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
3 citations
,
April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
Skin stem cells in hair follicles are important for touch sensation.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found a new way to isolate sweat glands from the scalp for study and culture.
24 citations
,
August 2021 in “Scientific Reports” Non-thermal plasma could help hair growth by activating key cell signals.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
Hair growth is maintained by specific cell signals.
180 citations
,
January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
10 citations
,
June 2021 in “EMBO reports” When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
April 2018 in “Journal of Investigative Dermatology” A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.