research GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
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research Five-alpha-reductase Inhibitors for prostate cancer prevention.
5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
research Hair Restoration Surgery: The State of the Art
Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.
research Intermittent Use of Testosterone Inactivating Pharmaceuticals Using Finasteride Prolongs the Time Off Period
Using finasteride with TIP extends time off period for prostate cancer patients.
research Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research Patients with specific skin disorders who are affected by COVID ‐19: What do experiences say about management strategies? A systematic review
Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.
research Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity
Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
research Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies
Stem cell treatments may improve burn wound healing.
research Risk of erectile dysfunction associated with use of 5-α reductase inhibitors for benign prostatic hyperplasia or alopecia: population based studies using the Clinical Practice Research Datalink
Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.
research Postscreening follow-up of the Finnish Prostate Cancer Screening Trial on putative prostate cancer risk factors: vitamin and mineral use, male pattern baldness, pubertal development and non-steroidal anti-inflammatory drug use
Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
research Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes
Wnt10b helps hair follicle cells mature and produce pigment.
research Finasteride induced gynecomastia: Case report and review of the literature
Finasteride for hair loss may cause gynecomastia; doctors should inform patients.
research The zombie commodity: hair and the politics of its globalization
The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.
research Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles
Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia
Genetic marker rs12558842 strongly linked to male hair loss.
research HaCaT Cell Proliferation Influenced by Melatonin
Melatonin affects skin cell growth differently based on how much and how long it's used.
research Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia: possible mechanism via VEGF induction
Topical tofacitinib may grow hair better than minoxidil by increasing VEGF and reducing inflammation.
research A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection
The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
research Management of unwanted hair in females
Different hair removal methods have pros and cons, and more evidence is needed to prove laser treatments work.
research Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
research Integrated safety analysis of baricitinib in adults with severe alopecia areata from two randomized clinical trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development
Ozone therapy might improve cancer treatment and reduce its side effects.
research Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Malva verticillataseed extracts upregulate the Wnt pathway in human dermal papilla cells
Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.
research Effects of Oral Finasteride on Erectile Function in a Rat Model
Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells
Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
research Ganoderma lucidum is an inhibitor of testosterone-induced prostatic hyperplasia in rats
Ganoderma lucidum may help treat enlarged prostate in rats.