252 citations
,
April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
185 citations
,
August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
135 citations
,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
131 citations
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August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
127 citations
,
June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
125 citations
,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
105 citations
,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
103 citations
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January 2011 in “Blood” Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
96 citations
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September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
60 citations
,
July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
59 citations
,
October 2020 in “Stem Cell Reviews and Reports” Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.
54 citations
,
October 2024 in “Nature Communications” Molybdenum oxide nanozymes can effectively treat and monitor acute kidney injury by reducing oxidative stress.
54 citations
,
August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
49 citations
,
October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
28 citations
,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
27 citations
,
November 2021 in “Scientific Reports” Men are more affected by COVID-19 due to differences in immune responses and protein expression.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
21 citations
,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
20 citations
,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
18 citations
,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
17 citations
,
April 2021 in “Biointerface Research in Applied Chemistry” Nanostructured lipid carriers are promising for improving drug delivery in medicine and food.
17 citations
,
January 2019 in “Journal of cancer” The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
16 citations
,
February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
13 citations
,
September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
11 citations
,
March 2024 in “Cell and Tissue Research” Telocytes have potential in therapy and tissue regeneration, but challenges in identification and cultivation remain.
4 citations
,
April 2021 in “Experimental and Molecular Medicine” The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
3 citations
,
December 2021 in “Physiological Research” Low testosterone may increase COVID-19 severity in men.
2 citations
,
April 2019 in “Proceedings of Singapore Healthcare” Collaborative care between physicians and pharmacists improved medication management for rheumatoid arthritis without raising costs.
2 citations
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January 2014 in “Elsevier eBooks” The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.