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Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Wildebeest stress and hormone levels are influenced by food availability, human presence, and reproductive cycles.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

PCOS involves hormonal and metabolic issues, increasing risks for diabetes and heart disease, and requires lifestyle changes and medication for management.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

Stress worsens symptoms and body changes in women with PCOS, especially during COVID-19.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Treating hyperprolactinemia can help manage PCOS symptoms.

The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.