April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.
April 2021 in “Journal of Investigative Dermatology” IL-15 helps protect hair follicles from immune attacks and encourages hair growth.
April 2021 in “Journal of Investigative Dermatology” The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.
7 citations
,
December 2024 in “Antibiotics” Cathelicidins could treat skin issues but face challenges like safety and resistance.
63 citations
,
September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
38 citations
,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
22 citations
,
October 2004 in “Journal of Investigative Dermatology” The gene causing hair loss and heart issues in rough coat mice is still unknown.
2 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.
April 2012 in “KSBB Journal” Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
79 citations
,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
37 citations
,
October 2009 in “Dermatology” Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
24 citations
,
May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
19 citations
,
January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
15 citations
,
October 1999 in “British Journal of Dermatology” Collagen remodeling is more active during hair growth stages.
14 citations
,
October 2021 in “Dermatology and Therapy” UV exposure accelerates skin aging by altering elastin, leading to wrinkles.
6 citations
,
August 2024 in “Biomacromolecules” The model helps test drugs for clubfoot fibrosis by mimicking cell environments and shows minoxidil reduces harmful collagen links.
5 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.
3 citations
,
January 1988 Minoxidil helps hair grow, especially in people with mild hair loss.
2 citations
,
January 1987 in “Acta Agriculturae Scandinavica” Certain chelators lighten mink skin and hair, increase skin elasticity, and disrupt hair growth without affecting fur quality.
May 2026 in “Bioactive Materials” The microneedle patch helps regrow hair by restoring enzyme function in hair follicles.
March 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
September 2023 in “International journal of biomedicine” Minoxidil might help treat acne scars by reducing collagen buildup.
December 2019 in “International journal of engineering applied science and technology” Tridax procumbens, a weed, has various medicinal properties including wound healing and antibacterial effects.
January 1989 in “Clinical and Experimental Dermatology” The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.
158 citations
,
June 2014 in “Journal of Lipid Research” Lysophospholipids can act as anti-inflammatory agents through specific receptors, but more research is needed.
13 citations
,
April 1964 in “PubMed” Phosphatide distribution in mouse skin remains consistent in both normal and cancerous growths.
January 2005 in “Life sciences” Targeting LPA could help treat skin disorders.
49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
24 citations
,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
31 citations
,
October 2010 in “Progress in lipid research” LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.