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Persistent Major Alopecia Following Adjuvant Docetaxel for Breast Cancer: Incidence, Characteristics, and Prevention with Scalp Cooling

research Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

19 citations , June 2018 in “Breast Cancer Research and Treatment”

Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.

research Histological and Gene Expression Analysis of the Effects of Menopause Status and Hormone Therapy on the Vaginal Introitus and Labia Majora

7 citations , January 2019 in “Journal of clinical medicine research”

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

research Eruptive vellus hair cysts of the labia majora: detection of openings of the cysts to the epidermis by dermoscopy

9 citations , May 2013 in “European Journal of Dermatology”

Dermoscopy can non-invasively detect eruptive vellus hair cysts on the labia majora.

research Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

160 citations , July 2008 in “Experimental dermatology”

Melatonin protects the skin by scavenging free radicals and repairing DNA damage.

research Trichohyalin is a Potential Major Autoantigen in Human Alopecia Areata

66 citations , July 2010 in “Journal of Proteome Research”

Trichohyalin may trigger the immune response causing alopecia areata.

research Male balding is a major risk factor for severe COVID-19

29 citations , July 2020 in “Journal of The American Academy of Dermatology”

Men with severe balding have a higher risk of getting very sick from COVID-19.

research Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing

21 citations , October 2007 in “Journal of Investigative Dermatology”

Fetuin-A helps wounds heal without scars by promoting cell movement.

Male Balding as a Major Risk Factor for Severe COVID-19: A Possible Role for Targeting Androgens and Transmembrane Protease Serine 2 to Protect Vulnerable Individuals

research Male balding as a major risk factor for severe COVID-19: A possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals

6 citations , September 2020 in “Journal of The American Academy of Dermatology”

Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.

Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1Hi>-pyrido[4,3-bi>]indol-5(2Hi>)-yl)acetic Acid (Setipiprant/ACT-129968)

6 citations , September 2015 in “Journal of Medicinal Chemistry”

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
3 citations , March 2017 in “Regulatory toxicology and pharmacology”

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

research Hypoparathyroidism as the single major component for decades of autoimmune polyglandular syndrome type 1
2 citations , December 2020 in “Endocrinology, diabetes & metabolism case reports”

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

research Efficacy and Tolerability of a Hyaluronic Acid-Based Extracellular Matrix for Labia Majora Rejuvenation and Augmentation: A Pilot Study
April 2024 in “Curēus”

Sunekos® effectively improves labia majora appearance and is well-tolerated.

research COMPARATIVE ANALYSIS OF MAJOR AND TRACE ELEMENT CONTENT IN THE HAIR OF CHILDREN WITH DOWN SYNDROME AND OBESITY
January 2019 in “Trace Elements in Medicine (Moscow)”

Hair analysis may help monitor health in children with Down syndrome and obesity.

research Analysis of Skin, Hair and Nail Diseases in the Adults with Beta Thalassemia Major
March 2018 in “Gazi medical journal”

Adults with Beta Thalassemia Major are more likely to have skin, hair, and nail disorders.

research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
225 citations , April 2018 in “Journal of Investigative Dermatology”

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
49 citations , October 2009 in “Cancer research”

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

research Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss
38 citations , February 2012 in “British Journal of Dermatology”

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

research COVID-19 infection is a major cause of acute telogen effluvium
25 citations , August 2021 in “Irish Journal of Medical Science (1971 -)”

COVID-19 infection can significantly cause temporary hair loss.

research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
15 citations , June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

research Copious Pre‐Ejaculation: Small Glands—Major Headaches
9 citations , April 2007 in “Journal of Andrology”

Excessive pre-ejaculation can be treated with certain medications.

research Serum testosterone levels in surgeons during major head and neck cancer surgery: a suppositional study
6 citations , April 2011 in “British journal of oral & maxillofacial surgery/British journal of oral and maxillofacial surgery”

Surgeons' testosterone levels significantly increase during major head and neck cancer surgeries.

research Age- and sex-dependence of five major elements in the development of human scalp hair
3 citations , December 2019 in “Biomaterials Research/Biomaterials research”

Calcium and magnesium in hair increase with age and are higher in adult women.

research A response to “Male balding is a major risk factor for severe COVID-19”
2 citations , October 2020 in “Journal of The American Academy of Dermatology”

The authors suggest that scalp hair might protect against COVID-19 and call for more research on scalp health and the virus.

research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry
1 citations , March 2012 in “Acta Pharmaceutica Sinica B”

New methods can detect finasteride's major urinary metabolite in urine for up to 49 hours.

research ^{Androgenetic Alopecia Is not Associated With Major Vascular Comorbidities: A Retrospective Case‐Control Study of 8230 Patients}
December 2024 in “JEADV Clinical Practice”

Androgenetic alopecia is linked to a higher risk of varicose veins, especially in men, but not to major vascular diseases.

research Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth-Inducing Properties In Vivo and In Vitro via the Wnt/β-Catenin Pathway in Dermal Papilla Cells
March 2024 in “Nutrients”

Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.

research Do androgens really play a major role in the pathophysiology of androgenetic alopecia?
January 2024 in “Brazilian Journal of Hair Health”

Androgens might not be the only major factor in hair loss; other elements could also be important.

research A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome
June 2022 in “International Journal of Health Sciences (IJHS)”

Understanding proteins linked to PCOS symptoms can improve diagnosis and treatment.

research Management of Advanced Prostate Cancer Undergoing Major Shift
June 2011 in “Oncology times”

New treatments are making advanced prostate cancer management more complex but also more hopeful.

research Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development
318 citations , October 1998 in “The Journal of Cell Biology”

Keratin 17 is important for skin development and may help define skin cell types.

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Research

research Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

research Histological and Gene Expression Analysis of the Effects of Menopause Status and Hormone Therapy on the Vaginal Introitus and Labia Majora

research Eruptive vellus hair cysts of the labia majora: detection of openings of the cysts to the epidermis by dermoscopy

research Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

research Trichohyalin is a Potential Major Autoantigen in Human Alopecia Areata

research Male balding is a major risk factor for severe COVID-19

research Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing

research Male balding as a major risk factor for severe COVID-19: A possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1Hi>-pyrido[4,3-bi>]indol-5(2Hi>)-yl)acetic Acid (Setipiprant/ACT-129968)

research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite

research Hypoparathyroidism as the single major component for decades of autoimmune polyglandular syndrome type 1

research Efficacy and Tolerability of a Hyaluronic Acid-Based Extracellular Matrix for Labia Majora Rejuvenation and Augmentation: A Pilot Study

research COMPARATIVE ANALYSIS OF MAJOR AND TRACE ELEMENT CONTENT IN THE HAIR OF CHILDREN WITH DOWN SYNDROME AND OBESITY

research Analysis of Skin, Hair and Nail Diseases in the Adults with Beta Thalassemia Major

research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin

research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

research Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss

research COVID-19 infection is a major cause of acute telogen effluvium

research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature

research Copious Pre‐Ejaculation: Small Glands—Major Headaches

research Serum testosterone levels in surgeons during major head and neck cancer surgery: a suppositional study

research Age- and sex-dependence of five major elements in the development of human scalp hair

research A response to “Male balding is a major risk factor for severe COVID-19”

research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry

research ^{Androgenetic Alopecia Is not Associated With Major Vascular Comorbidities: A Retrospective Case‐Control Study of 8230 Patients}

research Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth-Inducing Properties In Vivo and In Vitro via the Wnt/β-Catenin Pathway in Dermal Papilla Cells

research Do androgens really play a major role in the pathophysiology of androgenetic alopecia?

research A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome

research Management of Advanced Prostate Cancer Undergoing Major Shift

research Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development