January 2022 in “Cosmoderma” Using oral minoxidil and dutasteride together can quickly increase hair growth and volume with minimal side effects.
58 citations
,
December 2018 in “Nature Communications” Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
299 citations
,
March 2001 in “Journal of Investigative Dermatology” Male pattern baldness is linked to specific genetic variations in the androgen receptor gene.
191 citations
,
December 2003 in “Journal of Investigative Dermatology” Male pattern baldness is largely genetic, linked to the androgen receptor gene, and may relate to certain health issues.
169 citations
,
June 1998 in “Journal of Investigative Dermatology” Male pattern baldness is likely caused by multiple genes, not just 5α-reductase genes.
138 citations
,
August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
133 citations
,
February 2017 in “PLoS Genetics” Genetic factors can help predict male pattern baldness risk.
71 citations
,
May 1991 in “Clinical and Experimental Dermatology” Young men with male pattern baldness lose hair density over time without treatment.
68 citations
,
February 1990 in “Journal of Applied Social Psychology” Bald men are often viewed more negatively and as older than they really are.
64 citations
,
March 2017 in “Nature communications” Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
57 citations
,
February 2014 in “Experimental Dermatology” Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
57 citations
,
July 1987 in “Journal of The American Academy of Dermatology” Stopping minoxidil treatment resumes balding; continuous use needed for results.
53 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
51 citations
,
November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
51 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.
48 citations
,
May 2015 in “PLOS ONE” DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.
42 citations
,
April 2009 in “Human Genetics” A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.
41 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
40 citations
,
July 2008 in “Drug Discovery Today” Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
37 citations
,
October 2015 in “European Journal of Human Genetics” Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
28 citations
,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
26 citations
,
January 2013 in “BMJ Open” Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.
21 citations
,
January 2000 in “Aesthetic Plastic Surgery” Researchers created a new system to classify male baldness, finding six types and a common hairline shape, to improve hair loss treatments.
20 citations
,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
19 citations
,
January 2001 in “Dermatology + psychosomatics” The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
17 citations
,
January 2016 in “American Journal of Epidemiology” Men with male pattern baldness have a higher risk of dying from prostate cancer.
12 citations
,
September 2021 in “PLoS ONE” WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.
12 citations
,
November 2019 in “PLoS ONE” Male-pattern baldness is weakly linked to some heart disease risk factors but not a strong indicator for heart disease.
5 citations
,
August 2018 in “International Journal of Dermatology” Men with sleep apnea and low iron levels are more likely to have male-pattern baldness, especially if they have a family history of hair loss.