research Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
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research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Distinct mechanisms underlie pattern formation in the skin and skin appendages
Different processes create patterns in skin and things like hair and feathers.
research Parsing patterns: Emerging roles of tissue self-organization in health and disease
Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
research Integrated Single-Cell Analysis Reveals Spatially and Temporally Dynamic Heterogeneity in Fibroblast States during Wound Healing
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing
Controlling immune responses with biomaterials can reduce scarring and improve skin regeneration.
research Making Waves with Hairs
Skin patterns are formed by simple reaction-diffusion mechanisms.
research At the dawn of hair research – testing the limits of hair follicle regeneration
Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
research Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice
Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
research Delayed Collagen Production without Myofibroblast Formation Contributes to Reduced Scarring in Adult Skin Microwounds
Microthermal wounds heal with less scarring due to delayed collagen production and minimal inflammation.
research Wound-Induced Hair Neogenesis Model
Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.
research The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection
Skin symptoms can be a sign of COVID-19 and may worsen with stress.
research At the crossroads of 2 alopecias: Androgenetic alopecia pattern of hair regrowth in patients with alopecia areata treated with oral Janus kinase inhibitors
JAK inhibitors help hair regrowth but not fully effective for androgenetic alopecia.
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research Skin-Associated Cartilage Is a Distinct Type of Lipid-Filled Tissue
Lipocartilage is a new type of tissue that affects hair growth and cartilage regeneration.
research Aged Skin Cells Nurture Stem Cells toward Regeneration
Aged skin cells can help hair growth by stimulating stem cells.
research Author response: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning
Understanding hair follicle interactions can help treat male pattern baldness.
research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Methods and techniques for dissecting mechanical regulation of wound healing using photocrosslinkable biomaterials
research Ancestral Diversity of Skin Reaches Single-Cell Resolution
Ancestry affects skin healing, with non-Hispanic Black patients showing more healing-related fibroblasts than White patients.
research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis
Immune cells boost stem cell activity in hairy moles, causing more hair growth.
research Pharmacotherapy for diffuse alopecia
Selencin effectively reduces hair loss and improves hair health in diffuse alopecia.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
research 974 Single-cell analysis identifies heterogeneity of fibroblasts and myeloid-derived adipocytes in regenerating mouse skin wounds
Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
research Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency epidemiology, etiopathogenesis, clinical presentation, treatment – a systematic review
CAH requires a multidisciplinary approach, and while current treatments help, future therapies show promise.
research A Guide for Studying Spatiotemporal Variability in Murine Hair Cycle and Hair Growth Wave Patterns In Vivo
research CURRENT UNDERSTANDING OF VITILIGO: A COMPREHENSIVE LITERATURE REVIEW
Vitiligo is a systemic disease with psychological effects, and new treatments focus on personalized care.
research Six-Month Quality of Life and Health Outcomes After Bariatric Surgery: A Prospective Cohort Study from Latvia
Bariatric surgery improved quality of life and health in six months, but hair loss was common.