September 2022 in “Farmacja Polska” Biotin is important for health, but taking extra usually doesn't help unless you're deficient.
72 citations
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October 1988 in “Archives of Disease in Childhood” Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
26 citations
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May 1984 in “Journal of Parenteral and Enteral Nutrition” Biotin supplements restored hair and resolved symptoms in a woman with biotin deficiency.
6 citations
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January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
3 citations
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January 2021 in “Molecular genetics & genomic medicine” The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
89 citations
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January 2020 in “PubMed” Early detection and biotin treatment improve outcomes for biotinidase deficiency.
9 citations
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December 1987 in “Archives of Dermatology” Two genetic disorders affect biotin metabolism, causing severe skin, hair, and metabolic issues.
184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
50 citations
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May 1985 in “The journal of pediatrics/The Journal of pediatrics” Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.
10 citations
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April 2020 in “Clinics in Dermatology” Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
22 citations
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September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
74 citations
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July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
55 citations
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December 1987 in “Archives of Dermatology” Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
2 citations
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January 1997 in “Journal of Clinical Biochemistry and Nutrition” Biotin deficiency causes severe hair loss and weight reduction in germ-free mice.
73 citations
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October 2001 in “Epilepsia” Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
21 citations
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June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
12 citations
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January 1987 in “Ophthalmic Paediatrics and Genetics” Early diagnosis and treatment of biotinidase deficiency are crucial to prevent vision problems.
5 citations
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October 2019 in “Giornale italiano di dermatologia e venereologia” Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.
August 2021 in “Journal of medical science and clinical research” An infant with seizures and hair loss was diagnosed with biotinidase deficiency and treated successfully with biotin.
12 citations
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September 2011 in “BMJ Case Reports” Quick diagnosis and biotin treatment can dramatically improve biotinidase deficiency symptoms.
May 2022 in “Endocrine practice” High-dose biotin can cause false thyroid test results; stop taking biotin two days before testing to avoid errors.
6 citations
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September 1996 in “Journal of the European Academy of Dermatology and Venereology” Biotin supplements may help hair regrowth in alopecia areata patients with low biotinidase activity.
1 citations
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November 2011 in “Turkish Journal of Dermatology” Biotin treatment improved hair and skin issues in a child with biotinidase deficiency.
15 citations
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May 2006 in “Brain & development” Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
1 citations
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September 1996 in “Journal of the European Academy of Dermatology and Venereology” Biotin supplements may help hair regrowth in some alopecia areata patients.
23 citations
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January 1991 in “Journal of Animal Science” Biotin supplementation in sow diets is unnecessary.
31 citations
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December 1997 in “Developmental Medicine & Child Neurology” Biotinidase deficiency can cause vision and walking problems in children and can improve with biotin treatment.
5 citations
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May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.