May 2024 in “Pigment International” Several treatments are effective for pigmentary disorders like vitiligo and melasma.
February 2025 in “Jurnal Kedokteran Brawijaya” Autologous skin cell transplantation speeds up healing and xenografts improve skin color in burn care.
421 citations
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September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
April 2019 in “Journal of Investigative Dermatology” Fractional photothermolysis helps wounds heal with minimal scarring.
31 citations
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February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
157 citations
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December 2015 in “Journal of the American Academy of Dermatology” A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.
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January 2008 in “Indian Journal of Dermatology” Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
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March 2023 in “Lasers in Surgery and Medicine” Ablative fractional laser treatment nearly matches the gene reduction effects of topical vismodegib in skin cancer.
17 citations
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April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
1 citations
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April 2016 in “PubMed” Epidermis and dermis cells together can regenerate hair follicles.
11 citations
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May 2021 in “Journal of Cosmetic Dermatology” Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.
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March 2011 in “Stem Cell Reviews and Reports”
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March 2015 in “PubMed” Scalp micropigmentation, a cosmetic tattoo technique, is a promising non-surgical treatment for hair and scalp deformities, despite potential complications.
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July 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
25 citations
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October 1985 in “Archives of Ophthalmology” The pigment in black eyeliner can spread in the skin and may cause permanent eyelash loss.
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August 1987 in “Archives of Dermatology” Langerhans' cells are not involved in hair depigmentation in these mice.
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June 1998 in “Developmental Biology” More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
Microneedling and PRP are safe and effective for skin rejuvenation in people with skin of color, with fewer side effects than laser treatments.
April 2018 in “Journal of Investigative Dermatology” The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.
September 2017 in “Journal of Investigative Dermatology” Photodynamic therapy can potentially remove nonpigmented hair by damaging hair follicles.
1 citations
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August 2024 in “Heliyon” Hair follicle stem cells can become melanocytes to help treat skin depigmentation.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.
July 2025 in “Dermatologic Surgery”
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November 2017 in “Journal of Glaucoma” Latanoprost eye drops may cause skin depigmentation.
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August 2013 in “Facial Plastic Surgery Clinics of North America” SMP is a medical tattoo for hair loss, improving appearance and camouflaging scars, but requires skill and has limitations.
August 2022 in “Journal of Cosmetic Dermatology” Understanding key techniques is crucial for natural-looking scalp micropigmentation.
August 2023 in “Skin Research and Technology” Platelet-rich plasma (PRP) may improve healing in chronic wounds and vitiligo and promote hair regrowth, but more research is needed.