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Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Hormones and genes affect hair growth and male baldness.

New genes and pathways are important for testosterone production and male sexual development.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

Including androgens in hormone therapy may lower breast cancer risk.

Testosterone treatment may affect heart response to stress in transgender men.

Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.

Estrogen alone can lower testosterone in some transfeminine people.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Genetics may play a significant role in gender dysphoria.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Men are increasingly interested in cosmetic treatments that enhance masculinity and address aging without downtime, with tailored approaches for different ethnicities and a focus on hair restoration and body contouring.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Significant facial gender transformation requires surgery, not nonsurgical methods.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Facial hair is crucial for transgender men's gender identity and transition.

In post-menopausal women, signs of increased male hormones should be checked for possible ovarian cancer.

A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

Hormones beyond androgens may cause acne and hair loss.