Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
12 citations
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October 2018 in “International Journal of Women's Dermatology” Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.
September 2018 in “Boletín médico del Hospital Infantil de México” Medical care for transgender youth should be individualized and supportive.
May 2025 in “Oxford Academix (Oxford)” Dermatology trainees lack standardized guidelines and education for treating testosterone-induced skin conditions in transmasculine individuals.
8 citations
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June 2016 in “PubMed” Finasteride is effective and safe for treating hidradenitis suppurativa in both adults and some younger patients.
September 2025 in “Journal of the American Academy of Dermatology” Sublingual minoxidil significantly improves hair growth in transgender individuals on testosterone therapy.
1 citations
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October 2021 in “LGBT health” The review discusses how facial masculinization surgeries are done and their costs.
1 citations
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January 2001 in “Endocrine Practice” Topical finasteride may help treat facial hirsutism in women.
September 2023 in “Journal of The American Academy of Dermatology” Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.
October 2010 in “Informa Healthcare eBooks”
October 2020 in “Проблемы эндокринологии” Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.
April 2000 in “Indian Journal of Dermatology” January 2000 in “DOAJ (DOAJ: Directory of Open Access Journals)”
24 citations
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March 2018 in “Pediatric Dermatology” Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.
April 2023 in “Research Square (Research Square)” A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.
January 2019 in “The Annals of Thoracic Surgery” The document concludes that careful planning and execution of facial gender affirmation surgery after at least 12 months of hormonal therapy can improve the quality of life for transgender individuals.
96 citations
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September 2008 in “Seminars in Cutaneous Medicine and Surgery” Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
228 citations
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February 2003 in “Urology” Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.
January 2016 in “AACE Clinical Case Reports” Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.
January 2004 in “Elsevier eBooks” Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.
1 citations
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January 2017 in “Tohoku journal of experimental medicine” A woman's mature cystic teratoma caused her virilization by producing testosterone.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
16 citations
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June 2022 in “Transgender Health” Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.
18 citations
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November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
January 2010 in “Springer eBooks”
506 citations
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March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
January 2026 in “JCEM Case Reports” Genetics may play a significant role in gender dysphoria.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
57 citations
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January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.